Application of nanotechnology in bladder cancer diagnosis and therapeutic drug delivery

被引:2
作者
Li, Hang-zhuo [1 ]
Zhu, Jian [1 ]
Weng, Guo-jun [1 ]
Li, Jian-jun [1 ]
Li, Lei [2 ]
Zhao, Jun-wu [1 ]
机构
[1] Xi An Jiao Tong Univ, Sch Life Sci & Technol, Key Lab Biomed Informat Engn, Minist Educ, Xian 710049, Peoples R China
[2] Jiaotong Univ, Affiliated Hosp Xian 1, Dept Urol, Xian 710061, Peoples R China
基金
中国国家自然科学基金;
关键词
INTRAVESICAL INSTILLATION; RADICAL CYSTECTOMY; ANTITUMOR-ACTIVITY; CELL CARCINOMA; NANOPARTICLES; DISEASE; SCATTERING; DESIGN; SYSTEM; QUANTIFICATION;
D O I
10.1039/d3tb01323e
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Bladder cancer (BC) is one of the most common malignant tumors in the urinary system, and its high recurrence rate is a great economic burden to patients. Traditional diagnosis and treatment methods have the disadvantages of insufficient targeting, obvious side effects and low sensitivity, which seriously limit the accurate diagnosis and efficient treatment of BC. Due to their small size, easy surface modification, optical properties such as plasmon resonance, and surface enhanced Raman scattering, good electrical conductivity and photothermal conversion properties, nanomaterials have great potential application value in the realization of specific diagnosis and targeted therapy of BC. At present, the application of nanomaterials in the diagnosis and treatment of BC is attracting great attention and achieving rich research results. Therefore, this paper summarizes the recent research on nanomaterials in the diagnosis and treatment of BC, clarifies the existing advantages and disadvantages, and provides theoretical guidance for promoting the accurate diagnosis and efficient treatment of BC.
引用
收藏
页码:8368 / 8386
页数:19
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