Oncological and functional outcomes of transoral laser surgery for hypopharyngeal carcinoma

被引:2
作者
Casanueva, Rodrigo [1 ]
Lopez, Fernando [1 ,2 ,3 ,4 ]
Garcia-Cabo, Patricia [1 ,2 ,3 ,4 ]
Alvarez-Marcos, Cesar [1 ,2 ,3 ,4 ]
Llorente, Jose Luis [1 ,2 ,3 ,4 ]
Rodrigo, Juan Pablo [1 ,2 ,3 ,4 ]
机构
[1] Univ Oviedo, Hosp Univ Cent Asturias, Dept Otolaryngol, Av Roma SN, Oviedo 33011, Spain
[2] Inst Invest Sanitaria Principado Asturias, Oviedo, Spain
[3] Ctr Invest Biomed Red Canc CIBERONC, ISCIII, Madrid, Spain
[4] Univ Oviedo, Inst Univ Oncol Principado Asturias, Oviedo, Spain
关键词
Hypopharyngeal cancer; Transoral; Laser; Head and neck cancer; Surgery; SQUAMOUS-CELL CARCINOMA; DEFINITIVE RADIOTHERAPY; CANCER; MICROSURGERY; PRESERVATION; FEASIBILITY; T1;
D O I
10.1007/s00405-022-07622-1
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background Surgical resection or radiotherapy (RT) are standard approaches for early-staged hypopharyngeal squamous cell carcinoma (HPSCC). Transoral laser microsurgery (TOLMS) seems to provide good oncological and functional results with few local complications. The aim of our study was to analyze the outcomes of TOLMS, with or without neck dissection or RT, in the treatment of HPSCC in a tertiary referral center. Methods A retrospective study was conducted in patients with early T-category (T1-T2) HPSCC treated by TOLMS. Results A total of 34 patients were included in the study. The series includes 17 (50%) T1 and 17 (50%) T2 classified tumors. The 5-year overall survival and disease-specific survival rates were 51% and 66%, respectively, with a 5-year local control rate of 92%. All patients reassumed oral diet and none of them had a tracheostomy at the end of the follow-up. Conclusions TOLMS offers an effective treatment option in terms of oncologic control and function preservation in locally circumscribed HPSCC.
引用
收藏
页码:829 / 837
页数:9
相关论文
共 33 条
  • [1] Asymptomatic swallowing disorders may be present in individuals with laryngeal and hypopharyngeal cancer treated with chemo-radiotherapy
    Alvarez-Marcos, Cesar
    Benito, Andrea Vicente
    Fernandez, Agueda Gayol
    Pedregal-Mallo, Daniel
    Rodriguez, Paloma Sirgo
    Rabanal, Liliana Santamarina
    Llorente, Jose Luis
    Lopez, Fernando
    Rodrigo, Juan Pablo
    [J]. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2022, 279 (02) : 995 - 1001
  • [2] Transoral laser microsurgery as standard approach to hypopharyngeal cancer. Survival analysis in a hospital based population
    Breda, Eduardo
    Catarino, Raquel
    Monteiro, Eurico
    [J]. ACTA OTORRINOLARINGOLOGICA ESPANOLA, 2018, 69 (01): : 1 - 7
  • [3] Oncologic results of transoral laser microsurgery for squamous cell carcinoma of the posterior pharyngeal wall
    Canis, Martin
    Wolff, Hendrik A.
    Ihler, Friedrich
    Matthias, Christoph
    Steiner, Wolfgang
    [J]. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2015, 37 (02): : 156 - 161
  • [4] Chen LY, 2015, ANTICANCER RES, V35, P1735
  • [5] The Emerging Role of Robotic Surgery among Minimally Invasive Surgical Approaches in the Treatment of Hypopharyngeal Carcinoma: Systematic Review and Meta-Analysis
    De Virgilio, Armando
    Iocca, Oreste
    Malvezzi, Luca
    Di Maio, Pasquale
    Pellini, Raul
    Ferreli, Fabio
    Cugini, Giovanni
    Colombo, Giovanni
    Spriano, Giuseppe
    [J]. JOURNAL OF CLINICAL MEDICINE, 2019, 8 (02):
  • [6] Surgical treatment for hypopharynx carcinoma: Feasibility, mortality, and results
    Eckel, HE
    Staar, S
    Volling, P
    Sittel, C
    Damm, M
    Jungehuelsing, M
    [J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2001, 124 (05) : 561 - 569
  • [7] Herrero PGC, 2017, ACTA OTORRINOLAR ESP, V68, P328, DOI 10.1016/j.otorri.2016.11.001
  • [8] Hypopharyngeal cancer: A state of the art review
    Garneau, Jonathan C.
    Bakst, Richard L.
    Miles, Brett A.
    [J]. ORAL ONCOLOGY, 2018, 86 : 244 - 250
  • [9] A Contemporary Review of Indications for Primary Surgical Care of Patients With Squamous Cell Carcinoma of the Head and Neck
    Gourin, Christine G.
    Johnson, Jonas T.
    [J]. LARYNGOSCOPE, 2009, 119 (11) : 2124 - 2134
  • [10] Oncologic results and quality of life in patients with squamous cell carcinoma of hypopharynx after transoral laser microsurgery
    Hung, Li-Ting
    Huang, Hsin-I
    Wang, Ling-Wei
    Yang, Muh-Hwa
    Chu, Pen-Yuan
    [J]. LASERS IN SURGERY AND MEDICINE, 2018, 50 (02) : 117 - 124