Imaging Methods: Magnetic Resonance Imaging

被引:21
作者
Thomas, Katharine E. [1 ]
Fotaki, Anastasia [2 ]
Botnar, Rene M. [2 ,3 ,4 ]
Ferreira, Vanessa M. [1 ,5 ]
机构
[1] Univ Oxford, Univ Oxford Ctr Clin Magnet Resonance Res OCMR, Radcliffe Dept Med, Div Cardiovasc Med, Oxford, England
[2] Kings Coll London, St Thomas Hosp, Sch Biomed Engn & Imaging Sci, Dept Biomed Engn, London, England
[3] Pontificia Univ Catolica Chile, Escuela Ingn, Santiago, Chile
[4] Millennium Inst Intelligent Healthcare Engn, Santiago, Chile
[5] John Radcliffe Hosp, Univ Oxford Ctr Clin Magnet Resonance Res OCMR, Level 0, Oxford OX3 9DU, England
基金
英国工程与自然科学研究理事会;
关键词
cardiac imaging techniques; immune system; inflammation; magnetic resonance imaging; DIFFUSE MYOCARDIAL FIBROSIS; IMMUNE-CELL INFILTRATION; IRON-OXIDE; HYPERTROPHIC CARDIOMYOPATHY; SUPERPARAMAGNETIC PARTICLES; TISSUE CHARACTERIZATION; ALLOGRAFT-REJECTION; INVERSION-RECOVERY; EUROPEAN-SOCIETY; MOUSE MODEL;
D O I
10.1161/CIRCIMAGING.122.014068
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Myocardial inflammation occurs following activation of the cardiac immune system, producing characteristic changes in the myocardial tissue. Cardiovascular magnetic resonance is the non-invasive imaging gold standard for myocardial tissue characterization, and is able to detect image signal changes that may occur resulting from inflammation, including edema, hyperemia, capillary leak, necrosis, and fibrosis. Conventional cardiovascular magnetic resonance for the detection of myocardial inflammation and its sequela include T2-weighted imaging, parametric T1- and T2-mapping, and gadolinium-based contrast-enhanced imaging. Emerging techniques seek to image several parameters simultaneously for myocardial tissue characterization, and to depict subtle immune-mediated changes, such as immune cell activity in the myocardium and cardiac cell metabolism. This review article outlines the underlying principles of current and emerging cardiovascular magnetic resonance methods for imaging myocardial inflammation.
引用
收藏
页数:16
相关论文
共 101 条
[1]   Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis -: Comparison of different approaches [J].
Abdel-Aty, H ;
Boyé, P ;
Zagrosek, A ;
Wassmuth, R ;
Kumar, A ;
Messroghli, D ;
Bock, P ;
Dietz, R ;
Friedrich, MG ;
Schulz-Menger, J .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (11) :1815-1822
[2]   Metabolic pathways in T cell activation and lineage differentiation [J].
Almeida, Luis ;
Lochner, Matthias ;
Berod, Luciana ;
Sparwasser, Tim .
SEMINARS IN IMMUNOLOGY, 2016, 28 (05) :514-524
[3]   Hyperpolarized 13C magnetic resonance imaging for noninvasive assessment of tissue inflammation [J].
Anderson, Stephanie ;
Grist, James T. ;
Lewis, Andrew ;
Tyler, Damian J. .
NMR IN BIOMEDICINE, 2021, 34 (03)
[4]   Proof-of-Principle Demonstration of Direct Metabolic Imaging Following Myocardial Infarction Using Hyperpolarized 13C CMR [J].
Apps, Andrew ;
Lau, Justin Y. C. ;
Miller, Jack J. J. J. ;
Tyler, Andrew ;
Young, Liam A. J. ;
Lewis, Andrew J. M. ;
Barnes, Gareth ;
Trumper, Claire ;
Neubauer, Stefan ;
Rider, Oliver J. ;
Tyler, Damian J. .
JACC-CARDIOVASCULAR IMAGING, 2021, 14 (06) :1285-1288
[5]   Hyperpolarised magnetic resonance for in vivo real-time metabolic imaging [J].
Apps, Andrew ;
Lau, Justin ;
Peterzan, Mark ;
Neubauer, Stefan ;
Tyler, Damian ;
Rider, Oliver .
HEART, 2018, 104 (18) :1484-+
[6]   Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR [J].
Ardenkjaer-Larsen, JH ;
Fridlund, B ;
Gram, A ;
Hansson, G ;
Hansson, L ;
Lerche, MH ;
Servin, R ;
Thaning, M ;
Golman, K .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (18) :10158-10163
[7]   Clinical Performance of High-Resolution Late Gadolinium Enhancement Imaging With Compressed Sensing [J].
Basha, Tamer A. ;
Akcakaya, Mehmet ;
Liew, Charlene ;
Tsao, Connie W. ;
Delling, Francesca N. ;
Addae, Gifty ;
Ngo, Long ;
Manning, Warren J. ;
Nezafat, Reza .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2017, 46 (06) :1829-1838
[8]   Imaging of myocarditis and inflammatory cardiomyopathies [J].
Biere, Loic ;
Piriou, Nicolas ;
Ernande, Laura ;
Rouzet, Francois ;
Lairez, Olivier .
ARCHIVES OF CARDIOVASCULAR DISEASES, 2019, 112 (10) :630-641
[9]   Cardiovascular magnetic resonance physics for clinicians: part II [J].
Biglands, John D. ;
Radjenovic, Aleksandra ;
Ridgway, John P. .
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, 2012, 14
[10]   Multifunctional MR monitoring of the healing process after myocardial infarction [J].
Boenner, Florian ;
Jacoby, Christoph ;
Temme, Sebastian ;
Borg, Nadine ;
Ding, Zhaoping ;
Schrader, Juergen ;
Floegel, Ulrich .
BASIC RESEARCH IN CARDIOLOGY, 2014, 109 (05)