Diagnostic and Prognostic Role of Delta Neutrophil Index (DNI), With Emphasis on Gastrointestinal Disorders

被引:0
作者
Daemi, Amin [1 ]
Yonden, Zafer [1 ]
Yousefi, Yavar [2 ]
Hosseini, Seyyedeh Touran [3 ]
Dogus, Yusuf [1 ]
Karaogullarindan, Umit [4 ]
机构
[1] Cukurova Univ, Dept Med Biochem, Fac Med, Adana, Turkiye
[2] Granen Med Ctr, Malmo, Sweden
[3] Cukurova Univ, Inst Nat & Appl Sci, Dept Biotechnol, Adana, Turkiye
[4] Cukurova Univ, Fac Med, Dept Gastroenterol, Adana, Turkiye
来源
MEDICINA BALEAR | 2023年 / 38卷 / 05期
关键词
Delta Neutrophil Index (DNI); Prognosis; Infectious Conditions; Gastrointestinal Disorders; IMMATURE GRANULOCYTE; BACTEREMIA; INFECTION; MORTALITY; MARKER;
D O I
10.3306/AJHS.2023.38.05.55
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: A brand-new biomarker for diagnosis and prognosis for a variety of inflammatory or infectious conditions is the delta neutrophil index (DNI). DNI is a laboratory index that is determined by dividing the total number of peripheral blood neutrophils by the number of immature granulocytes. However, there are few studies that have examined the potential use of DNI as a prognostic biomarker in gastrointestinal disorders and their associated infections. The purpose of this study was to explore the role of delta neutrophil index (DNI) as a biomarker to determine the prognosis of infectious conditions, especially in gastrointestinal diseases. Methods: The research is a bibliographic review. To review the articles, from the databases PubMed, Science Direct, Scopus, Google Scholar, etc., and based on the inclusion criteria, case reports, cohorts and numerous clinical studies used in a period of mostly 4 years (2019-2023) were selected. The final sample used in this review included 120 articles. Results and conclusion: The results showed that DNI may be considered as a primary and reliable biomarker for diagnosis, prognosis, initial triage, surgical outcomes, various infections, as well as predicting the severity of pediatric and gynecological conditions and cardiopulmonary or gastrointestinal disorders and etc.
引用
收藏
页码:55 / 60
页数:6
相关论文
共 29 条
[1]   The delta neutrophil index (DNI) as a prognostic marker for mortality in adults with sepsis: a systematic review and meta-analysis [J].
Ahn, Chiwon ;
Kim, Wonhee ;
Lim, Tae Ho ;
Cho, Youngsuk ;
Choi, Kyu-Sun ;
Jang, Bo-Hyoung .
SCIENTIFIC REPORTS, 2018, 8
[2]   The Delta Neutrophil Index is an Early Predictive Marker of Acute Pyelonephritis in Patients with Ureteral Stone [J].
Barut, Osman ;
Demirkol, Mehmet Kutlu ;
Bilecan, Enes Baki ;
Sahinkanat, Tayfun ;
Resim, Sefa .
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2020, 30 (11) :1149-1154
[3]   The use of delta neutrophil index and myeloperoxidase index as diagnostic predictors of strangulated mechanical bowel obstruction in the emergency department [J].
Cha, Yong Sung ;
Lee, Kang Hyun ;
Lee, Jong Wook ;
Choi, Eun Hee ;
Kim, Hyung Il ;
Kim, Oh Hyun ;
Cha, Kyoung Chul ;
Kim, Hyun ;
Hwang, Sung Oh .
MEDICINE, 2016, 95 (48) :e5481
[4]   Delta neutrophil index as a predictor of disease severity, surgical outcomes, and mortality rates in gastrointestinal diseases Rationale for a meta-analysis of diagnostic test accuracy [J].
Choi, Jae Ho ;
Bang, Chang Seok ;
Lee, Jae Jun ;
Baik, Gwang Ho .
MEDICINE, 2019, 98 (35) :e17059
[5]  
Durak D, 2022, EUR REV MED PHARMACO, V26, P4238, DOI 10.26355/eurrev_202206_29060
[6]   Usefulness of delta neutrophil index as a biomarker to predict postoperative complication in patients who underwent esophagectomy A case-control study [J].
Gong, Seong Chan ;
Ryu, Hoon ;
Jang, Ji Young .
MEDICINE, 2021, 100 (51) :E28311
[7]   Delta neutrophil index is an independent predictor of mortality in septic acute kidney injury patients treated with continuous renal replacement therapy [J].
Han, In Mi ;
Yoon, Chang-Yun ;
Shin, Dong Ho ;
Kee, Youn Kyung ;
Han, Seung Gyu ;
Kwon, Young Eun ;
Park, Kyoung Sook ;
Lee, Mi Jung ;
Oh, Hyung Jung ;
Park, Jung Tak ;
Han, Seung Hyeok ;
Kang, Shin-Wook ;
Yoo, Tae-Hyun .
BMC NEPHROLOGY, 2017, 18
[8]   Newly designed delta neutrophil index-to-serum albumin ratio prognosis of early mortality in severe sepsis [J].
Hwang, Yoon Jung ;
Chung, Sung Phil ;
Park, Yoo Seok ;
Chung, Hyun Soo ;
Lee, Hye Sun ;
Park, Jong Woo ;
Lee, Jong Wook ;
Hong, Jung Hwa ;
You, Je Sung ;
Park, Incheol .
AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2015, 33 (11) :1577-1582
[9]   Identification of the robust predictor for sepsis based on clustering analysis [J].
Jang, Jae Yeon ;
Yoo, Gilsung ;
Lee, Taesic ;
Uh, Young ;
Kim, Juwon .
SCIENTIFIC REPORTS, 2022, 12 (01)
[10]   Delta neutrophil index as a promising prognostic marker of emergent surgical intervention for acute diverticulitis in the emergency department [J].
Kang, Hee Seung ;
Choi, Yong Sung ;
Park, Kyung Hye ;
Hwang, Sung Oh .
PLOS ONE, 2017, 12 (11)