Updated Review and Clinical Recommendations for the Diagnosis and Treatment of Patients with Retroperitoneal Sarcoma by the Spanish Sarcoma Research Group (GEIS)

被引：7

作者：

Alvarez Alvarez, Rosa ^{[1
]}

Manzano, Aranzazu ^{[2
]}

Agra Pujol, Carolina ^{[3
]}

Artigas Raventos, Vicente ^{[4
]}

Correa, Raquel ^{[5
]}

Cruz Jurado, Josefina ^{[6
]}

Fernandez, Juan Angel ^{[7
]}

Garcia del Muro, Xavier ^{[8
]}

Gonzalez, Jose Antonio ^{[4
]}

Hindi, Nadia ^{[9
,10
,11
]}

Lozano Lominchar, Pablo ^{[12
]}

Martinez-Trufero, Javier ^{[13
]}

Mendez, Ramiro ^{[14
]}

Munoz, Mercedes ^{[15
]}

Munoz Casares, Cristobal ^{[16
]}

Orbis Castellanos, Francisco ^{[17
]}

Orellana Fernandez, Ruth ^{[18
]}

Paniagua Gonzalez, Miguel ^{[19
]}

Redondo, Andres ^{[20
]}

Valverde Morales, Claudia ^{[21
]}

Asencio, Jose Manuel ^{[12
]}

机构：

[1] Hosp Univ Gregorio Maranon, Med Oncol Dept, Inst Invest Sanitaria Gregorio Maranon, Madrid 28007, Spain

[2] Hosp Univ Clin San Carlos, Med Oncol Dept, Madrid 28040, Spain

[3] Univ Complutense Madrid, Hosp Univ Gregorio Maranon, Pathol Dept, Madrid 28007, Spain

[4] Univ Autonoma Barcelona, Hosp Univ St Pau, Surg Dept, Barcelona 08035, Spain

[5] Hosp Virgen Victoria, Radiat Oncol Dept, Malaga 29010, Spain

[6] Hosp Univ Canarias, Med Oncol Dept, Santa Cruz De Tenerife 38320, Spain

[7] Hosp Virgen Arrixaca, Surg Dept, Sarcoma Multidisciplinary Unit, Murcia 30120, Spain

[8] Inst Catalan Oncol Hosp, Med Oncol Dept, Sarcoma Multidisciplinary Unit, Idibell, Barcelona 08908, Spain

[9] Fdn Jimenez Diaz Univ Hosp, Med Oncol Dept, Madrid 28040, Spain

[10] Hosp Gen Villalba, Med Oncol Dept, Madrid 28400, Spain

[11] Univ Autonoma Madrid UAM, Hlth Res Inst Fdn Jimenez Diaz IIS FJD, Madrid 28040, Spain

[12] Univ Complutense Madrid, Hosp Univ Gregorio Maranon, Surg Dept, Madrid 28040, Spain

[13] Hosp Univ Miguel Servet, Med Oncol Dept, Zaragoza 50009, Spain

[14] Hosp Univ Clin San Carlos, Radiol Dept, Madrid 28040, Spain

[15] Univ Complutense Madrid, Hosp Univ Gregorio Maranon, Radiat Oncol Dept, Madrid 28007, Spain

[16] Hosp San Juan Dios, Surg Dept, Cordoba 14012, Spain

[17] Hosp Univ & Politecn La Fe, Surg Dept, Sarcoma Multidisciplinary Unit, Valencia 46026, Spain

[18] Hosp Univ St Creu & St Pau, Pathol Dept, Barcelona 08025, Spain

[19] Univ Complutense Madrid, Hosp Univ Gregorio Maranon, Radiol Dept, Madrid 28007, Spain

[20] Hosp Univ La Paz, Med Oncol Dept, IdiPAZ, Madrid 28046, Spain

[21] Vall DHebron Univ Hosp, Med Oncol Dept, Barcelona 08035, Spain

来源：

CANCERS | 2023年 / 15卷 / 12期

基金：

英国科研创新办公室;

关键词：

retroperitoneal sarcoma; soft tissue sarcoma; retroperitoneum; multidisciplinary board; reference centers; SOFT-TISSUE SARCOMA; RANDOMIZED PHASE-II; PROGNOSTIC-FACTORS; RADIATION-THERAPY; EUROPEAN ORGANIZATION; 1ST-LINE TREATMENT; RADIOTHERAPY; GEMCITABINE; MULTICENTER; RESECTION;

D O I：

10.3390/cancers15123194

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Simple Summary The treatment of retroperitoneal sarcomas poses significant challenges due to their infrequency, clinical and histologic heterogeneity, and unique anatomical location. We provide an updated review on the management of retroperitoneal sarcoma and issue clear and concise recommendations for the treatment of the main clinical situations encountered in this disease. Soft tissue sarcomas (STS) are an uncommon and biologically heterogeneous group of tumors arising from mesenchymal cells. The incidence is estimated at five cases per 100,000 people per year. Retroperitoneal sarcomas (RPS) account for 10-15% of all STS, and their management depends on their anatomical characteristics and histotype. Due to their very low incidence, it is recommended that RPS be treated in reference centers and evaluated by an experienced multidisciplinary team (MDT). In Spain, the Spanish Group for Research in Sarcomas (GEIS) brings together experts from various specialties to promote research on sarcomas and improve treatment results. This paper summarizes the GEIS recommendations for the diagnosis, treatment, and follow-up of patients with RPS.

引用

页数：23

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