Incidence, risk and protective factors for suicide mortality among patients with major depressive disorder

被引:18
作者
Chiu, Chih-Chiang [1 ,2 ,3 ]
Liu, Hsing-Cheng [1 ,2 ,3 ]
Li, Wei-Hsin [1 ]
Tsai, Shang-Ying [2 ,3 ]
Chen, Chiao-Chicy [1 ,4 ,5 ]
Kuo, Chian-Jue [1 ,2 ,3 ,6 ]
机构
[1] Taipei City Hosp, Taipei City Psychiat Ctr, Taipei, Taiwan
[2] Taipei Med Univ, Coll Med, Sch Med, Dept Psychiat, Taipei, Taiwan
[3] Taipei Med Univ Hosp, Psychiat Res Ctr, Taipei, Taiwan
[4] Mackay Mem Hosp, Dept Psychiat, Taipei, Taiwan
[5] Mackay Med Coll, Dept Psychiat, Taipei, Taiwan
[6] Taipei City Hosp, Taipei City Psychiat Ctr, Dept Gen Psychiat, 309 Sung Te Rd, Taipei 110, Taiwan
关键词
Risk factor; Protective factor; Suicide; Major depressive disorder; Standardised mortality ratio; COMPLETED SUICIDE; PREDICTORS;
D O I
10.1016/j.ajp.2022.103399
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Aim: Patients with major depression have greater suicide mortality, but there is no data on the standardised mortality ratio (SMR) and factors for suicide of major depression for Asian countries. This research estimates the SMR and the risk and protective factors for suicide mortality in patients with major depression in a large-scale Asian cohort.Methods: Patients with major depression (N = 1978) admitted to a psychiatric hospital in Taiwan between 1985 and 2008 were enrolled as the study cohort. When the cohort was linked to the national mortality database, 415 deceased patients were identified. Of these 415 deaths, 107 were from suicide. Nested case-control with risk sampling was used, where each case was matched with two controls. Clinical information was collected through a standardised chart review process. The SMR for suicide mortality was estimated, and a conditional logistic regression analysis was performed to determine risk and protective factors for suicide.Results: Patients with major depression had high all-cause and suicide mortality, with SMRs of 3.9 and 35.4, respectively. Agitation (adjusted risk ratio [aRR] = 2.85, P = 0.058), restlessness (aRR = 15.05, P = 0.045) and previous suicide attempts (aRR = 4.48, P = 0.004) were identified as risk factors for suicide mortality. By contrast, those with employment (aRR = 0.15, P = 0.003) or loss of interest (aRR = 0.32, P = 0.04) had lower risk.Conclusions: Patients with depression exhibited higher suicide mortality. Clinical staff should pay close attention to risk and protective factors to reduce suicide risk.
引用
收藏
页数:7
相关论文
共 28 条
[1]   Long-term suicide risk of depression in the Lundby cohort 1947-1997 -: severity and gender [J].
Bradvik, L. ;
Mattisson, C. ;
Bogren, M. ;
Nettelbladt, P. .
ACTA PSYCHIATRICA SCANDINAVICA, 2008, 117 (03) :185-191
[2]  
Breslow N E, 1987, IARC Sci Publ, P1
[3]   MORTALITY IN MAJOR AFFECTIVE-DISORDER - RELATIONSHIP TO SUBTYPE OF DEPRESSION [J].
BUCHHOLTZHANSEN, PE ;
WANG, AG ;
KRAGHSORENSEN, P .
ACTA PSYCHIATRICA SCANDINAVICA, 1993, 87 (05) :329-335
[4]   Regional Changes in Charcoal-Burning Suicide Rates in East/Southeast Asia from 1995 to 2011: A Time Trend Analysis [J].
Chang, Shu-Sen ;
Chen, Ying-Yeh ;
Yip, Paul S. F. ;
Lee, Won Jin ;
Hagihara, Akihito ;
Gunnell, David .
PLOS MEDICINE, 2014, 11 (04)
[5]   Suicidality in the geriatric population [J].
Chattun, Mohammad Ridwan ;
Amdanee, Nousayhah ;
Zhang, Xiangrong ;
Yao, Zhijian .
ASIAN JOURNAL OF PSYCHIATRY, 2022, 75
[6]   The diffusion of a new method of suicide: charcoal-burning suicide in Hong Kong and Taiwan [J].
Chen, Ying-Yeh ;
Yip, Paul S. F. ;
Lee, Carmen K. M. ;
Gunnell, David ;
Wu, Kevin Chien-Chang .
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, 2015, 50 (02) :227-236
[7]  
CHENG ATA, 1995, ARCH GEN PSYCHIAT, V52, P594
[8]   Risks of all-cause and suicide mortality in mental disorders: a meta-review [J].
Chesney, Edward ;
Goodwin, Guy M. ;
Fazel, Seena .
WORLD PSYCHIATRY, 2014, 13 (02) :153-160
[9]   Predictors and incidence rate of suicide re-attempt among suicide attempters: A prospective study [J].
Esmaeili, Elham Davtalab ;
Farahbakhsh, Mostafa ;
Sarbazi, Ehsan ;
Khodamoradi, Farzad ;
Fam, Saber Gaffari ;
Azizi, Hosein .
ASIAN JOURNAL OF PSYCHIATRY, 2022, 69
[10]   Indicators of suicide over 10 years in a specialist mood disorders unit sample [J].
Gladstone, GL ;
Mitchell, PB ;
Parker, G ;
Wilhelm, K ;
Austin, MP ;
Eyers, K .
JOURNAL OF CLINICAL PSYCHIATRY, 2001, 62 (12) :945-+