Severe and fatal neonatal infections linked to a new variant of echovirus 11, France, July 2022 to April 2023

被引：41

作者：

Grapin, Mathilde ^{[1
]}

Mirand, Audrey ^{[2
,3
]}

Pinquier, Didier ^{[4
]}

Basset, Aurelie ^{[5
]}

Bendavid, Matthieu ^{[1
]}

Bisseux, Maxime ^{[2
,3
]}

Jeannoel, Marion ^{[6
]}

Kireche, Berengere ^{[7
]}

Kossorotoff, Manoelle ^{[8
]}

L'Honneur, Anne-Sophie ^{[9
]}

Robin, Lila

Ville, Yves ^{[10
]}

Renolleau, Sylvain ^{[1
]}

Lemee, Veronique ^{[11
]}

Jarreau, Pierre-Henri ^{[5
]}

Desguerre, Isabelle ^{[8
]}

Lacaille, Florence ^{[12
]}

Leruez-Ville, Marianne ^{[13
]}

Gullame, Clemence ^{[14
]}

Henquell, Cecile ^{[2
,3
]}

Lapillonne, Alexandre ^{[15
]}

Schuffenecker, Isabelle ^{[6
]}

Aubart, Melodie ^{[8
,16
]}

机构：

[1] Paris Cite Univ, Necker Enfants Malad Univ Hosp, AP HP, Paediat Intens Care Unit, Paris, France

[2] Clermont Ferrand Univ Hosp, French Reference Ctr Enteroviruses & Parechovirus, 3IHP Infect Inflammat & Interact Hotes Pathogenes, Coordinat Lab, Clermont Ferrand, France

[3] Auvergne Univ, Team Epidemiol & Pathophysiol Enterovirus Infect, LMGE UMR CNRS 6023, Clermont Ferrand, France

[4] Rouen Univ Hosp, Neonatal & Paediat Intens Care Units, Rouen, France

[5] Paris Cite Univ, Cochin Port Royal Univ Hosp, AP HP, Neonatal Intens Care Unit, Paris, France

[6] Hosp Civils Lyon, French Reference Ctr Enteroviruses & Parechoviruse, Virol Dept, Associated Lab, Lyon, France

[7] Orleans Reg Hosp, Neonatal & Paediat Intens Care Units, Orleans, France

[8] Paris Cite Univ, Necker Enfants Malad Univ Hosp, AP HP, Paediat Neurol Dept, Paris, France

[9] Paris Cite Univ, Cochin Univ Hosp, AP HP, Virol Lab, Paris, France

[10] Paris Cite Univ, Necker Enfants Malad Univ Hosp, Obstet & Fetal Med Dept, AP HP, Paris, France

[11] Rouen Univ Hosp, Virol Dept, Rouen, France

[12] Univ Paris, Necker Enfants Malad Univ Hosp, AP HP, Pediat Gastroenterol Hepatol Nutr Unit, Paris, France

[13] Paris Cite Univ, Necker Enfants Malad Univ Hosp, AP HP, Clin Microbiol Lab & Virol Unit, Paris, France

[14] Orleans Hosp, Microbiol Lab, Orleans, France

[15] Paris Cite Univ, Necker Enfants Malad Univ Hosp, AP HP, Neonatal Intens Care Unit, Paris, France

[16] Imagine Inst, Necker Branch, Inst Natl St & Rech Med U1163, Lab Human Genet Infect Dis, Paris, France

来源：

EUROSURVEILLANCE | 2023年 / 28卷 / 22期

关键词：

SURVEILLANCE;

D O I：

10.2807/1560-7917.ES.2023.28.22.2300253

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3-5 days-old and had severe sepsis and liver failure. This new variant, detected in France since April 2022, is still circulating and has caused more fatal neonatal enterovirus infec-tions in 2022 and 2023 (8/496; 1.6%, seven associ-ated with echovirus 11) compared with 2016 to 2021 (7/1,774; 0.4%). National and international alerts are warranted.

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