Fractional Exhalation Nitric Oxide (FeNO) changes in cystic fibrosis patients induced by compound honey syrup: a pretest-posttest clinical trial

被引：0

作者：

Sadr, Saeed ^{[1
]}

Tahermohammadi, Hanieh ^{[2
,3
]}

Kaveh, Shahpar ^{[4
]}

Khanbabaee, Ghamartaj ^{[1
]}

Tabatabaei, Seyed Ahmad ^{[1
]}

Choopani, Rasool ^{[4
]}

Rouzbahani, Arian Karimi ^{[5
]}

Fadavi, Nafise ^{[6
]}

Derikvandi, Shima ^{[7
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Mofid Childrens Hosp, Dept Pediat Pulmonol, Tehran, Iran

[2] Shahid Beheshti Univ Med Sci, Natl Res Inst TB & Lung Dis NRITLD, Chron Resp Dis Res Ctr, Tehran, Iran

[3] Universal Sci Educ & Res Network USERN, Persian Med Network PMN, Tehran, Iran

[4] Shahid Beheshti Univ Med Sci, Sch Tradit Med, Dept Tradit Med, Tehran, Iran

[5] Lorestan Univ Med Sci, Student Res Comm, Khorramabad, Iran

[6] Iran Univ Med Sci, Rajaei Cardiovasc Med & Res Ctr, Tehran, Iran

[7] Student Univ Tehran, Fac Vet Med, Tehran, Iran

来源：

BMC PULMONARY MEDICINE | 2023年 / 23卷 / 01期

关键词：

Cystic fibrosis; Compound honey syrup; FeNO; Persian Medicine; TRANSMEMBRANE CONDUCTANCE REGULATOR; PEDIATRIC-PATIENTS; CROCUS-SATIVUS; DORNASE-ALPHA; GENISTEIN; CFTR; ACTIVATION; THERAPY; SAFFRON; BIOMARKER;

D O I：

10.1186/s12890-023-02787-9

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Objective: To evaluate the effect of Persian medicine Syrup 'compound honey syrup (CHS)' on fractional exhalation nitric oxide (FENO) changes in patients with cystic fibrosis (CF).Study design: We conducted a before-after clinical trial on 70 CF patients. All patients received classical treatments for CF along with CHS (including honey, Ginger, cinnamon, saffron, cardamom and galangal), 5-10 cc (depending on the age and weight of patients) in 100 cc of warm boiled water twice a day, 30 min after meals. In this clinical trial, before and 12 weeks after the start of the CHS, FeNO test was evaluated.Results: From 70 patients were enrolled, 44 patients completed this 12-week course of treatment. At the end of the study, changes in FeNO was significantly different before and after treatment (P-value < 0.05). At the end of the study, no dangerous side effects of CHS was reported.Conclusions: This study revealed that CHS can be effective as a complementary and safe drug in the medication of CF patients.

引用

页数：7

共 1 条

[1] Fractional Exhalation Nitric Oxide (FeNO) changes in cystic fibrosis patients induced by compound honey syrup: a pretest–posttest clinical trial
Saeed Sadr
Hanieh Tahermohammadi
Shahpar Kaveh
Ghamartaj Khanbabaee
Seyed Ahmad Tabatabaei
Rasool Choopani
Arian Karimi Rouzbahani
Nafise Fadavi
Shima Derikvandi
BMC Pulmonary Medicine, 23

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