The 'Behavioral Balance Model': A new perspective on the aetiology and therapy of obesity

被引:6
作者
Schultes, Bernd [1 ,8 ]
Ernst, Barbara [1 ]
Hallschmid, Manfred [2 ,3 ,4 ]
Bueter, Marco [5 ,6 ]
Meyhoefer, Sebastian M. [4 ,7 ]
机构
[1] friendlyDocs Ltd, Metab Ctr St Gallen, St Gallen, Switzerland
[2] Univ Tubingen, Dept Med Psychol & Behav Neurobiol, Tubingen, Germany
[3] Univ Tubingen IDM, Inst Diabet Res & Metab Dis, Helmholtz Ctr Munich, Tubingen, Germany
[4] German Ctr Diabet Res DZD, Munchen Neuherberg, Germany
[5] Univ Hosp Zurich, Dept Surg & Transplantat, Zurich, Switzerland
[6] Spital Mannedorf, Dept Surg, CH-8708 Mannedorf, Switzerland
[7] Univ Lubeck, Inst Endocrinol & Diabet, Lubeck, Germany
[8] friendlyDocs Ltd, Metab Ctr St Gallen, CH-9016 St Gallen, Switzerland
基金
瑞士国家科学基金会;
关键词
antidiabetic drug; appetite control; bariatric surgery; GLP-1; analogue; obesity therapy; weight control; EATING BEHAVIOR; WEIGHT-LOSS; FOOD-INTAKE; BRAIN; CONSEQUENCES; DISORDERS; OUTCOMES; HEALTH; STIGMA; REWARD;
D O I
10.1111/dom.15271
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity is a debilitating disease of global proportions that necessitates refined, concept-driven therapeutic approaches. Policy makers, the public and even health care professionals, but also individuals with obesity harbour many misconceptions regarding this disease, which leads to prejudice, negative attitudes, stigmatization, discrimination, self-blame, and failure to provide and finance adequate medical care. Decades of intensive, successful scientific research on obesity have only had a very limited effect on this predicament. We propose a science-based, easy-to-understand conceptual model that synthesizes the complex pathogenesis of obesity including biological, psychological, social, economic and environmental aspects with the aim to explain and communicate better the nature of obesity and currently available therapeutic modalities. According to our integrative 'Behavioral Balance Model', 'top-down cognitive control' strategies are implemented (often with limited success) to counterbalance the increased 'bottom-up drive' to gain weight, which is triggered by biological, psycho-social and environmental mechanisms in people with obesity. Besides offering a deeper understanding of obesity, the model also highlights why there is a strong need for multimodal therapeutic approaches that may not only increase top-down control but also reduce a pathologically increased bottom-up drive.
引用
收藏
页码:3444 / 3452
页数:9
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