共 50 条
- [1] Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) β InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (15) : 6858 - 6868Chandrasekhar, JayaramanDick, RyanVan Veldhuizen, JoshuaKoditek, DavidLepist, Eve-IreneMcGrath, Mary E.Patel, LeenaPhillips, GarySedillo, KassandraSomoza, John R.Therrien, JosephTill, Nicholas A.Treiberg, JenniferVillasenor, Armando G.Zherebina, YelenaPerreault, Stephane
- [2] Discovery of the Potent Phosphoinositide 3-Kinase δ (PI3 K δ) InhibitorsCHEMISTRYSELECT, 2020, 5 (01): : 196 - 200Lei, TaoHong, YongweiChang, XinyueZhang, ZhiminLiu, XingguoHu, MiaoHuang, WenhaiYang, Haiyan
- [3] INCB050465 (Parsaclisib), a Novel Next-Generation Inhibitor of Phosphoinositide 3-Kinase Delta (PI3Kδ)ACS MEDICINAL CHEMISTRY LETTERS, 2019, 10 (11): : 1554 - +Yue, Eddy W.Li, Yun-LongDouty, BrentHe, ChunhongMei, SongWayland, BrianMaduskuie, ThomasFalahatpisheh, NikooSparks, Richard B.Polam, PadmajaZhu, WenyuGlenn, JosephFeng, HaoZhang, KeLi, YanlongHe, XinKatiyar, KamnaCovington, MaryanneFeldman, PatriciaShin, NiuWang, Kathy HeDiamond, SharonLi, YuKoblish, Holly K.Hall, LeslieScherle, PeggyYeleswaram, SwamyXue, Chu-BiaoMetcalf, BrianCombs, Andrew P.Yao, Wenqing
- [4] Discovery of a novel phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor against hematologic malignancies and theoretical studies on its PI3Kγ-specific binding mechanismsRSC ADVANCES, 2019, 9 (35) : 20207 - 20215Zhu, JingyuKe, KeXu, LeiJin, Jian
- [5] Phosphoinositide 3-kinase δ (PI3Kδ) in respiratory diseaseBIOCHEMICAL SOCIETY TRANSACTIONS, 2018, 46 : 361 - 369Stokes, Clare A.Condliffe, Alison M.
- [6] Identification of Novel Piperazinylquinoxaline Derivatives as Potent Phosphoinositide 3-Kinase (PI3K) InhibitorsPLOS ONE, 2012, 7 (08):Wu, PengSu, YiGuan, XianghongLiu, XiaowenZhang, JiankangDong, XiaowuHuang, WenhaiHu, Yongzhou
- [7] Kinase activity of phosphoinositide 3-kinase gamma (PI3Kγ) is important for neutrophil infiltration in inflammationFASEB JOURNAL, 2012, 26Sablad, MarcianoCastro, GlendaRozenkrants, NatashaNgo, KarenRao, TadimetiZhang, YanFung-Leung, Wai-Ping
- [8] Pharmacological properties of a potent inhibitor of the phosphatidylinositol 3-kinase (PI3k) familyANNALS OF ONCOLOGY, 2007, 18 : 23 - 23Raynaud, F.Eccles, S.Clarke, P.Hayes, A.Di-Stefano, F.Ahmed, Z.Guillard, S.Workman, P.
- [9] Modification of a dihydropyrrolopyrimidine phosphoinositide 3-kinase (PI3K) inhibitor to improve oral bioavailabilityBIOORGANIC & MEDICINAL CHEMISTRY, 2015, 23 (24) : 7650 - 7660Kawada, HatsuoEbiike, HirosatoTsukazaki, MasaoYamamoto, ShunKoyama, KoheiNakamura, MitsuakiMorikami, KenjiYoshinari, KiyoshiYoshida, MiyukiOgawa, KotaroShinma, NobuoTsukuda, TakuoOhwada, Jun
- [10] Elucidation of the mechanism of phosphoinositide 3-kinase (PI3K) inhibitor mediated dyserythropoiesis in rodentsTOXICOLOGY LETTERS, 2015, 238 (02) : S282 - S283Ledieu, D.Bunn, I.Rosner, E.Wuersch, K.Hopfer, U.