NHPI-Mediated Electrochemical α-Oxygenation of Amides to Benzimides

被引：11

作者：

Bai, Fang ^{[1
]}

Wang, Ning ^{[1
]}

Bai, Yinshan ^{[1
]}

Ma, Xiaowei ^{[1
]}

Gu, Chengzhi ^{[1
]}

Dai, Bin ^{[1
]}

Chen, Jianpeng ^{[2
]}

机构：

[1] Shihezi Univ, Sch Chem & Chem Engn, State Key Lab Incubat Base Green Proc Chem Engn, Shihezi 832000, Xinjiang Uygur, Peoples R China

[2] Hami Shuoyuan Chem Co Ltd, Hami 832000, Xinjiang Uygur, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 05期

基金：

中国国家自然科学基金;

关键词：

N-ACYL; ALPHA; BETA-UNSATURATED IMIDES; OXIDATION; ALDEHYDES; LACTAMS; HYDROXYPHTHALIMIDE; METHYLARENES; ALKYLAMIDES; ALKYLATION; ACYLATION;

D O I：

10.1021/acs.joc.2c02700

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This report describes a mild electrochemical alpha- oxygenation of a wide range of linear and cyclic benzamides mediated by N-hydroxyphthalimide (NHPI) in an undivided cell using O2 as the oxygen source and 2,4,6-trimethylpyridine perchlorate as an electrolyte. The radical scavenger experiment and the 18O labeling experiment were carried out, which indicated the involvement of a radical pathway and suggested O2 as an oxygen source in the imides, respectively.

引用

页码：2985 / 2998

页数：14

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