Gynostemma pentaphyllum an immortal herb with promising therapeutic potential: a comprehensive review on its phytochemistry and pharmacological perspective

被引：11

作者：

Ahmed, Aftab ^{[1
]}

Saleem, Muhammad Awais ^{[1
,2
]}

Saeed, Farhan ^{[3
]}

Afzaal, Muhammad ^{[3
]}

Imran, Ali ^{[3
]}

Nadeem, Muhammad ^{[4
]}

Ambreen, Saadia ^{[5
]}

Imran, Muhammad ^{[6
]}

Hussain, Muzzamal ^{[3
]}

Al Jbawi, Entessar ^{[7
]}

机构：

[1] Govt Coll Univ Faisalabad, Dept Nutr Sci, Faisalabad, Punjab, Pakistan

[2] Mirpur Univ Sci & Technol, Dept Human Nutr & Dietet, New Mirpur City, Azad Kashmir, Pakistan

[3] Govt Coll Univ Faisalabad, Dept Food Sci, Faisalabad, Punjab, Pakistan

[4] Univ Sargodha, Inst Food Sci & Nutr, Sargodha, Pakistan

[5] Univ Inst Food Sci & Technol, Univ Lahore, Lahore, Pakistan

[6] Univ Narowal, Dept Food Sci & Technol, Narowal, Pakistan

[7] MAAR, Agr Extens Directorate, Damascus, Syria

来源：

INTERNATIONAL JOURNAL OF FOOD PROPERTIES | 2023年 / 26卷 / 01期

关键词：

Gynostemma pentaphyllum; saponins; gypenosides; ergostanol; antioxidant; DAMMARANE-TYPE GLYCOSIDES; NF-KAPPA-B; MITOCHONDRIA-DEPENDENT PATHWAYS; TYPE-2; DIABETES-MELLITUS; CANCER SAS CELLS; CUCURBITACEAE PLANTS; SAPONIN CONSTITUENTS; ANTIOXIDANT ACTIVITIES; IN-VITRO; GYPENOSIDES;

D O I：

10.1080/10942912.2023.2185566

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Gynostemma pentaphyllum belongs to the family Cucurbitaceae which is native to China where it is also termed an immortal herb. It is an emerging herb gaining fame for its rich phytochemistry. It is loaded with superior phytochemicals with immense therapeutic potential. The key phytochemicals include saponins and sterols. Saponins are a wide class of bioactive found in Gynostemma pentaphyllum and 100 different saponins have been reported to date by different researchers in this herb. Several sterols have been demonstrated in this plant including ergostanol, sitosterol and stigmasterol. All these bioactive substances possess superior therapeutic and pharmacological properties that have been investigated in different studies as presented in this comprehensive review. Taxonomic classification, botanical description, and geographical distribution are briefly covered in the first section of this review. In contrast, the phytochemistry, therapeutic properties, and pharmacological features of Gynostemma pentaphyllum are thoroughly explained in the second section.

引用

页码：808 / 832

页数：25

共 118 条

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