Green Extraction, Phytochemical Profiling, and Biological Evaluation of Dysphania ambrosioides: An In Silico and In Vitro Medicinal Investigation

被引：13

作者：

Paudel, Namuna ^{[1
]}

Rai, Mansi ^{[2
]}

Adhikari, Santosh ^{[3
]}

Thapa, Arjun ^{[1
]}

Bharati, Samjhana ^{[1
]}

Maharjan, Binita ^{[1
]}

Shrestha, Ram Lal Swagat ^{[1
,4
]}

Rav, Kranti ^{[5
]}

Singh, Ajay Vikram ^{[6
,7
]}

机构：

[1] Tribhuvan Univ, Inst Sci & Technol, Dept Chem, Amrit Campus, Kathmandu, Nepal

[2] Cent Univ Rajasthan, Dept Microbiol, Ajmer, India

[3] Friedrich Alexander Univ Nuremberg Erlangen German, Chem, Erlangen, Germany

[4] Inst Nat Resources Innovat, Dept Chem, Kathmandu, Nepal

[5] Delta Biopharmaceut, Pharmacy, Manavali, Andhra Pradesh, India

[6] German Fed Inst Risk Assessment BfR, Dept Chem & Prod Safety, Berlin, Germany

[7] German Fed Inst Risk Assessment BfR, Dept Chem & Prod Safety, Max Dohrn Str 8-10, D-10589 Berlin, Germany

来源：

JOURNAL OF HERBS SPICES AND MEDICINAL PLANTS | 2024年 / 30卷 / 02期

关键词：

Dysphania ambrosioides; TFC; phytochemical screening; GC-MS; antibacterial; TPC; antioxidant; SUPERCRITICAL-FLUID EXTRACTION;

D O I：

10.1080/10496475.2023.2267467

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Parasitic and microbial infections present substantial health risks, requiring effective treatments amidst growing antibiotic resistance. This study delves into Dysphania ambrosioides medicinal properties, utilizing hydro distillation and ultrasonic methods for extraction, followed by GC-MS analysis. Assessments revealed potent anti-diabetic effects in the methanol extract, significant antioxidant activity in the DCM extract and oil, and resistance against Escherichia coli. This research underscores the potential of local flora for novel treatments, particularly in underdeveloped regions. It emphasizes the value of plant screening in bioprospecting efforts, suggesting further investigations into specific bioactive compounds for pharmaceutical applications.

引用

页码：97 / 114

页数：18

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