High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report

被引：0
作者：
Wu, Maoyuan [1 ]
Zhang, Wenwen [1 ]
He, Lianli [2 ]
Zhu, Ye [2 ]
Jiang, Xiaoling [2 ]
Zhang, Lixia [2 ]
Yuan, Xiwei [3 ]
Li, Tingchao [4 ]
机构：
[1] Zunyi Med Univ, Peoples Hosp Zunyi 1, Dept Gynecol & Obstet, Affiliated Hosp 3, Zunyi, Guizhou, Peoples R China
[2] Zunyi Med Univ, Peoples Hosp Zunyi 1, Dept Gynecol, Affiliated Hosp 3, Zunyi, Guizhou, Peoples R China
[3] Zunyi Med Univ, Affiliated Hosp 3, Peoples Hosp Zunyi 1, Dept Imaging, Zunyi, Peoples R China
[4] Zunyi Med Univ, Affiliated Hosp 3, Peoples Hosp Zunyi 1, Dept Pathol, Zunyi, Peoples R China
来源：
FRONTIERS IN ONCOLOGY | 2024年 / 14卷
关键词：
case report; multiple primary malignant neoplasms; cervical cancer; ovarian cancer; high-grade serous papillary carcinoma; CANCER; TUMORS;
D O I：
10.3389/fonc.2024.1298109
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Multiple primary malignant neoplasms are a rare gynecologic malignancy; particularly, cases originating from the heterologous organs, such as the ovary and cervix. Here, we report a case of two primary malignant neoplasms in a patient who had undergone laparoscopic radical hysterectomy + bilateral salpingo-oophorectomy + pelvic lymph node dissection + para-aortic lymphadenectomy + appendectomy + omentectomy + metastasectomy under general anesthesia. The patient experienced complete remission after six courses of postoperative chemotherapy with a standard Taxol and Carboplatin regimen. Genetic testing was performed to detect BRCA2 mutations, and poly (ADP-ribose) polymerase (PARP) inhibitors were used for maintenance therapy.
引用
收藏
页数：8
相关论文
共 34 条
[1]   The Rare Diagnosis of Synchronous Breast and Colonic Cancers: A Case Report and Review of Literature [J].
Asaad, Amira ;
Barron, Marina ;
Rasheed, Noreen ;
Idaewor, Philip ;
Al-Zawi, Abdalla Saad Abdalla .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (02)
[2]  
Casaubon J.T., 2022, StatPearls
[3]   ESMO-ESGO consensus conference recommendations on ovarian cancer: pathology and molecular biology, early and advanced stages, borderline tumours and recurrent disease [J].
Colombo, N. ;
Sessa, C. ;
du Bois, A. ;
Ledermann, J. ;
McCluggage, W. G. ;
McNeish, I. ;
Morice, P. ;
Pignata, S. ;
Ray-Coquard, I. ;
Vergote, I. ;
Baert, T. ;
Belaroussi, I. ;
Dashora, A. ;
Olbrecht, S. ;
Planchamp, F. ;
Querleu, D. ;
Baert, T. ;
Banerjee, S. ;
Belaroussi, I. ;
Blecharz, P. ;
Bruchim, I. ;
Cibula, D. ;
Colombo, N. ;
Concin, N. ;
Davidson, B. ;
Dashora, A. ;
Devouassoux-Shisheboran, M. ;
du Bois, A. ;
Ferrero, A. ;
Glasspool, R. ;
Gonzalez-Martin, A. ;
Heinzelmann-Schwarz, V. ;
Joly, F. ;
Kim, J. W. ;
Kridelka, F. ;
Ledermann, J. ;
Lorusso, D. ;
Mahner, S. ;
McCluggage, W. G. ;
McNeish, I. ;
Mikami, M. ;
Mirza, M. R. ;
Morice, P. ;
Nicum, S. ;
Olbrecht, S. ;
O'Donnell, D. M. ;
Pautier, P. ;
Planchamp, F. ;
Pignata, S. ;
Querleu, D. .
ANNALS OF ONCOLOGY, 2019, 30 (05) :672-705
[4]  
Copur Mehmet Sitki, 2019, Oncology (Williston Park), V33
[5]   Synchronous tumours of the female reproductive tract [J].
Gilks, C. Blake ;
Kommoss, Friedrich .
PATHOLOGY, 2018, 50 (02) :214-221
[6]  
He Y, 2022, Zhonghua Fu Chan Ke Za Zhi, V57, P352, DOI 10.3760/cma.j.cn112141-20220214-00086
[7]  
Huang KJ, 2022, AGING-US, V14, P3836, DOI 10.18632/aging.204047
[8]   Synchronous multiple primary malignant neoplasms in breast, kidney, and bilateral thyroid: A case report [J].
Jia, Miao-Miao ;
Yang, Bin ;
Ding, Chao ;
Yao, Ya-Rong ;
Guo, Jun ;
Yang, Hai-Bo .
WORLD JOURNAL OF CLINICAL CASES, 2023, 11 (07) :1513-1520
[9]   PARP inhibitors in ovarian cancer: Sensitivity prediction and resistance mechanisms [J].
Jiang, Xuan ;
Li, Xiaoying ;
Li, Weihua ;
Bai, Huimin ;
Zhang, Zhenyu .
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 23 (04) :2303-2313
[10]   PARP Inhibitors: Clinical Limitations and Recent Attempts to Overcome Them [J].
Kim, Dongha ;
Nam, Hye Jin .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (15)
1234