EVIDENCE OF ALTERED FEAR EXTINCTION LEARNING IN INDIVIDUALS WITH HIGH VACCINE HESITANCY DURING COVID-19 PANDEMIC

被引：9

作者：

Vicario, Carmelo M. ^{[1
]}

Makris, Stergios ^{[2
]}

Culicetto, Laura ^{[1
]}

Lucifora, Chiara ^{[3
,4
]}

Falzone, Alessandra ^{[1
]}

Martino, Gabriella ^{[5
]}

Ferraioli, Francesca ^{[1
]}

Nitsche, Michael A. ^{[6
]}

Avenanti, Alessio ^{[7
,8
,9
,10
]}

Craparo, Giuseppe ^{[11
]}

机构：

[1] Univ Messina, Dipartimento Sci Cognit Psicol Pedagogiche & Studi, Messina, Italy

[2] Edge Hill Univ, Dept Psychol, Liverpool, England

[3] Inst Technol & Cognit Sci ISTC CNR, I-00185 Rome, Italy

[4] Univ Bologna, Dept Philosophy & Commun, Bologna, Italy

[5] Univ Messina, Dept Clin & Expt Med, I-98122 Messina, Italy

[6] Leibniz Res Ctr Working Environm & Human Factors, Dept Psychol & Neurosci, D-44139 Dortmund, Germany

[7] Bielefeld Univ, Univ Clin Child & Adolescent Psychiat & Psychother, Univ Hosp OWL, Protestant Hosp Bethel Fdn, D-33617 Bielefeld, Germany

[8] Univ Clin Child & Adolescent Psychiat & Psychother, D-33617 Bielefeld, Germany

[9] Alma Mater Studiorum Univ Bologna, Ctr Studies & Res Cognit Neurosci, Dept Psychol Renzo Canestrari, Cesena Campus, I-47521 Cesena, Italy

[10] Neuropsicol & Cognit Neurosci Res Ctr CINIPSI Neur, UNnivers Catol Maule, Talca 3460000, Chile

[11] Cittadella Univ, UKE Kore Univ Enna, Fac Human & Social Sci, I-94100 Enna, Italy

来源：

CLINICAL NEUROPSYCHIATRY | 2023年 / 20卷 / 04期

关键词：

vaccine hesitancy; pavlovian fear conditioning; fear extinction learning; anxiety; inhibitory learning process; ACQUISITION; HUMANS;

D O I：

10.36131/cnfioritieditore20230417

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: A relevance of fear and concerns about vaccine development and its side effects are suggested to explain COVID-19 vaccine hesitancy. However, evidence supporting the phobic origin hypothesis of hesitancy for COVID-19 and other vaccinations remains indirect and elusive. Method: We addressed this issue by investigating the existence of a relationship between fear conditioning, extinction, and the respective vaccination hesitancy and anxiety scores in a group of 25 individuals. Results: Overall, we show that the general mechanism of fear extinction learning is impaired in individuals with high vaccine hesitancy. State and trait anxiety scores do not account for this result. Conclusions: These findings suggest that attitudes against vaccination could be linked to an altered inhibitory learning process.

引用

页码：364 / 369

页数：6

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