Mycochemical composition and antioxidant activity of root endophytic aquatic hyphomycetes isolated from the riparian area of Kumaun Himalaya, India

被引:0
作者
Pant, Prabha [1 ]
Sati, S. C. [1 ]
Kumar, Parikshit [2 ,3 ]
Koranga, Anjali [1 ]
机构
[1] Kumaun Univ, Dept Bot, DSB Campus, Naini Tal, Uttaranchal, India
[2] Harsh Vidya Mandir PG Coll, Dept Bot, Haridwar, Uttaranchal, India
[3] Harsh Vidya Mandir PG Coll, Dept Bot, Haridwar 247671, Uttaranchal, India
关键词
Antioxidant activity; endophyte; fungal extract; GC-MS analysis; Tetracladium setigerum;
D O I
10.1080/14786419.2023.2297406
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Endophytic fungi are essential sources of various bioactive natural compounds. The present study is aimed to investigate the chemical composition and antioxidant compounds of the root endophytic aquatic hyphomycetous fungi Tetracladium setigerum isolated from the roots of Barberries aristata growing in the riparian area of Nainital, Kumaun Himalaya. The chemical profiling was done by GC-MS analysis. The presence of 32 compounds characterised the fungal extract. 1, 2-Benzenedicarboxylic acid, diethyl ester; Bis(2-ethylhexyl) phthalate; and Bicyclo [3.2.1]octan-4-on-1-carbonsaeure,6-(6,10dimethyl-1,5,9-undecatrien-2-yl)-8-methyl-, ethyl ester were reported as major compounds in the ethyl acetate extract of T. setigerum. The antioxidant capacity of the extract was assessed by DPPH, MCA, and FRAP assay. In antioxidant analysis, the ethyl acetate extract of T. setigerum presents IC50, 42.34 mu g/ml, and 46.90 mu g/ml using DPPH and MCA, respectively. The tested extract also showed effective antioxidant activity 436.71 +/- 9.3 mg AAE/g of the dry extract using FRAP assay.
引用
收藏
页码:2348 / 2352
页数:5
相关论文
共 23 条
[1]   Fungi in the Marine Environment: Open Questions and Unsolved Problems [J].
Amend, Anthony ;
Burgaud, Gaetan ;
Cunliffe, Michael ;
Edgcomb, Virginia P. ;
Ettinger, Cassandra L. ;
Gutierrez, M. H. ;
Heitman, Joseph ;
Hom, Erik F. Y. ;
Ianiri, Giuseppe ;
Jones, Adam C. ;
Kagami, Maiko ;
Picard, Kathryn T. ;
Quandt, C. Alisha ;
Raghukumar, Seshagiri ;
Riquelme, Mertixell ;
Stajich, Jason ;
Vargas-Muniz, Jose ;
Walker, Allison K. ;
Yarden, Oded ;
Gladfelter, Amy S. .
MBIO, 2019, 10 (02)
[2]   A new problem. Contamination of botanicals by phthalates. Rapid detection tests [J].
Bianco, Armandodoriano ;
Venditti, Alessandro ;
Foddai, Sebastiano ;
Toniolo, Chiara ;
Nicoletti, Marcello .
NATURAL PRODUCT RESEARCH, 2014, 28 (02) :134-137
[3]   Biologically Active Secondary Metabolites from the Fungi [J].
Bills, Gerald F. ;
Gloer, James B. .
MICROBIOLOGY SPECTRUM, 2016, 4 (06)
[4]   Bioactive sesquiterpene, plasticizer, and phenols from the fungal endophytes of Polygonum chinense L. [J].
Das, Madhuchhanda ;
Prakash, Harischandra Sripathy ;
Nalini, Monnanda Somaiah .
ANNALS OF MICROBIOLOGY, 2018, 68 (10) :595-609
[5]   Reversal of P-glycoprotein-mediated paclitaxel resistance by new synthetic isoprenoids in human bladder cancer cell line [J].
Enokida, H ;
Gotanda, T ;
Oku, S ;
Imazono, Y ;
Kubo, H ;
Hanada, T ;
Suzuki, S ;
Inomata, K ;
Kishiye, T ;
Tahara, Y ;
Nishiyama, K ;
Nakagawa, M .
JAPANESE JOURNAL OF CANCER RESEARCH, 2002, 93 (09) :1037-1046
[6]  
Govindappa M., 2014, International Journal of Biological Pharmaceutical Research, V5, P861
[7]  
[郭毅 GUO Yi], 2008, [安徽农业科学, Journal of Anhui Agricultural Sciences], V36, P6356
[8]   Characterization and antioxidant activity of selenium-containing phycocyanin isolated from Spirulina platensis [J].
Huang, Z. ;
Guo, B. J. ;
Wong, R. N. S. ;
Jiang, Y. .
FOOD CHEMISTRY, 2007, 100 (03) :1137-1143
[9]   Endophytic fungi from medicinal plants: a treasure hunt for bioactive metabolites [J].
Kaul, Sanjana ;
Gupta, Suruchi ;
Ahmed, Maroof ;
Dhar, Manoj K. .
PHYTOCHEMISTRY REVIEWS, 2012, 11 (04) :487-505
[10]   Plant polyprenols and their biological activity [J].
Khidyrova, NK ;
Shakhidoyatov, KM .
CHEMISTRY OF NATURAL COMPOUNDS, 2002, 38 (02) :107-121