Azathioprine-induced lymphoma in a patient with Takayasu arteritis: A case report from Iraq

被引：0
作者：
Awadh, Nabaa Ihsan [1 ]
Al-Osami, Mohammed Hadi [2 ]
Hashim, Hashim Talib [3 ]
Al-Obaidi, Ahmed Dheyaa [3 ]
Al-Obaidi, Mustafa Najah [3 ]
Abdlkarim, Sumaya Abdulhasan [4 ]
机构：
[1] Baghdad Teaching Hosp, Internal Med Dept, Rheumatol Unit, Baghdad, Iraq
[2] Univ Baghdad, Coll Med, Dept Internal Med, Rheumatol Unit, Baghdad, Iraq
[3] Univ Baghdad, Coll Med, Baghdad, Iraq
[4] Baghdad Teaching Hosp, Dept Internal Med, Rheumatol Unit, Baghdad, Iraq
来源：
CLINICAL CASE REPORTS | 2023年 / 11卷 / 06期
关键词：
azathioprine; lymphadenopathy; lymphoma; Takayasu arteritis; THERAPY;
D O I：
10.1002/ccr3.7559
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Key Clinical MessageAzathioprine, used for vasculitis and connective tissue diseases, carries long-term cancer risks. This case report raises awareness among healthcare providers about such risks and emphasizes the need for taking necessary precautions to avoid them while treating such diseases. We present an Azathioprine-induced lymphoma case in a 51-year-old male patient with Takayasu arteritis who presented with painless cervical swelling, itching, weight loss, and decreased appetite. This case report aims to increase awareness of the potential long-term cancer risks associated with azathioprine use in the treatment of chronic diseases.
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页数：5
相关论文
共 15 条
[1]   Non-glucocorticoid drugs for the treatment of Takayasu's arteritis: A systematic review and meta-analysis [J].
Barra, Lillian ;
Yang, Grace ;
Pagnoux, Christian .
AUTOIMMUNITY REVIEWS, 2018, 17 (07) :683-693
[2]   Azathioprine: its uses in dermatology [J].
Chavez-Alvarez, Sonia ;
Herz-Ruelas, Maira ;
Villarreal-Martinez, Alejandra ;
Ocampo-Candiani, Jorge ;
Garza-Garza, Rubicela ;
Gomez-Flores, Minerva .
ANAIS BRASILEIROS DE DERMATOLOGIA, 2020, 95 (06) :731-736
[3]   Myasthenia Gravis [J].
Gilhus, Nils E. .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (26) :2570-2581
[4]   Long-term outcome of 251 patients with Takayasu arteritis on combination immunosuppressant therapy: Single centre experience from a large tertiary care teaching hospital in Southern India [J].
Goel, Ruchika ;
Danda, Debashish ;
Joseph, George ;
Ravindran, Raheesh ;
Kumar, Sathish ;
Jayaseelan, Visali ;
Jayaseelan, Lakshmanan ;
Bacon, Paul .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2018, 47 (05) :718-726
[5]   Takayasu arteritis: an update [J].
Keser, Gokhan ;
Aksu, Kenan ;
Direskeneli, Haner .
TURKISH JOURNAL OF MEDICAL SCIENCES, 2018, 48 (04) :681-697
[6]   Risk of Lymphoma in Patients With Inflammatory Bowel Disease Treated With Azathioprine and 6-Mercaptopurine: A Meta-analysis [J].
Kotlyar, David S. ;
Lewis, James D. ;
Beaugerie, Laurent ;
Tierney, Ann ;
Brensinger, Colleen M. ;
Gisbert, Javier P. ;
Loftus, Edward V., Jr. ;
Peyrin-Biroulet, Laurent ;
Blonski, Wojciech C. ;
Van Domselaar, Manuel ;
Chaparro, Maria ;
Sandilya, Sandipani ;
Bewtra, Meenakshi ;
Beigel, Florian ;
Biancone, Livia ;
Lichtenstein, Gary R. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (05) :847-U541
[7]  
Mohammadi O., 2022, STATPEARLS
[8]   Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis [J].
Munz, Martin ;
Pretscher, Dominik ;
Wilhelm, Martin ;
Holzgrabe, Ulrike ;
Soergel, Fritz ;
Birkmann, Josef .
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2018, 56 (03) :142-147
[9]   Effects of immunosuppressive and biological agents on refractory Takayasu arteritis patients unresponsive to glucocorticoid treatment [J].
Ohigashi, Hirokazu ;
Tamura, Natsuko ;
Ebana, Yusuke ;
Harigai, Masayoshi ;
Maejima, Yasuhiro ;
Ashikaga, Takashi ;
Isobe, Mitsuaki .
JOURNAL OF CARDIOLOGY, 2017, 69 (5-6) :774-778
[10]   Reducing the Toxicity of Long-Term Glucocorticoid Treatment in Large Vessel Vasculitis [J].
Palmowski, Andriko ;
Buttgereit, Frank .
CURRENT RHEUMATOLOGY REPORTS, 2020, 22 (12)
12