Single-Molecule Force Spectroscopy Reveals Cation-π Interactions in Aqueous Media Are Highly Affected by Cation Dehydration

被引：9

作者：

Di, Weishuai ^{[1
]}

Xue, Kai ^{[2
,3
,4
]}

Cai, Jun ^{[5
]}

Zhu, Zhenshu ^{[2
,3
]}

Li, Zihan ^{[2
,3
]}

Fu, Hui

Lei, Hai

Hu, Wenbing ^{[5
]}

Tang, Chun ^{[2
,3
]}

Wang, Wei ^{[6
,7
,8
]}

Cao, Yi ^{[1
,6
,7
,8
]}

机构：

[1] Univ Chinese Acad Sci, Wenzhou Inst, Wenzhou Key Lab Biophys, Wenzhou 325000, Zhejiang, Peoples R China

[2] Peking Univ, Beijing Natl Lab Mol Sci, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

[3] Peking Univ, PekingTsinghua Ctr Life Sci, Beijing 100871, Peoples R China

[4] Nanyang Technol Univ, Sch Phys & Math Sci, 21 Nanyang Link, Singapore 637371, Singapore

[5] Nanjing Univ, Sch Chem & Chem Engn, Dept Polymer Sci & Engn, Collaborat Innovat Ctr Chem Life Sci,Key Lab Coor, Nanjing 210023, Peoples R China

[6] Nanjing Univ, Dept Phys, Collaborat Innovat Ctr Adv Microstruct, Natl Lab Solid State Microstruct, Nanjing 210093, Peoples R China

[7] Nanjing Univ, Inst Brain Sci, Nanjing 210093, Peoples R China

[8] Nanjing Univ, Chem & Biomed Innovat Ctr, Nanjing 210093, Peoples R China

来源：

PHYSICAL REVIEW LETTERS | 2023年 / 130卷 / 11期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

SURFACE-TENSION; HYDRATION; BENZENE; POLYMER; ION; NANOMECHANICS; INTERFACES; INDUCTION; AROMATICS; ORIGIN;

D O I：

10.1103/PhysRevLett.130.118101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Cation-pi interactions underlie many important processes in biology and materials science. However, experimental investigations of cation-pi interactions in aqueous media remain challenging. Here, we studied the cation-pi binding strength and mechanism by pulling two hydrophobic polymers with distinct cation binding properties, i.e., poly-pentafluorostyrene and polystyrene, in aqueous media using single-molecule force spectroscopy and nuclear magnetic resonance measurement. We found that the interaction strengths linearly depend on the cation concentrations, following the order of Li+ < NH4+ < Na+ < K+. The binding energies are 0.03-0.23 kJ mol(-1) M-1. This order is distinct from the strength of cation-p interactions in gas phase and may be caused by the different dehydration ability of the cations. Taken together, our method provides a unique perspective to investigate cation-pi interactions under physiologically relevant conditions.

引用

页数：7

共 56 条

[1] Effect of Intramolecular Hydrogen Bonds on the Single-Chain Elasticity of Poly(vinyl alcohol): Evidencing the Synergistic Enhancement Effect at the Single-Molecule Level [J].