No Major Age Shift During the Second Wave of COVID-19: A Mortality Analysis at a Tertiary-Level Hospital

被引:0
作者
Prakash, Kelika [1 ]
Ganesh, Venkata [1 ]
Ayub, Arshad [1 ]
Aggarwal, Richa [1 ]
Singh, Yudhyavir [1 ]
Kumar, Shailendra [1 ]
Singh, Abhishek [1 ]
Soni, Kapil D. [1 ]
机构
[1] All India Inst Med Sci AIIMS, Dept Anaesthesiol Pain Med & Crit Care, New Delhi, India
关键词
COVID-19; mortality; pandemic; second wave; VENTILATION;
D O I
10.5152/TJAR.2023.22815
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Objective: The second wave of coronavirus epidemic affected India severely. We reviewed the in-hospital deaths during the second wave at a dedicated COVID hospital to better understand the clinical characteristics of patients who died during this period. Methods: Clinical charts of all patients who were admitted and died in-hospital due to COVID-19 between 1 April 2021 and 15 May 2021 were reviewed and clinical data were analysed. Results: The total number of patients admitted to hospital and the intensive care unit was 1438 and 306, respectively. The in-hospital and intensive care unit mortality was 9.3% (134 out of 1438 patients) and 37.6% (115 out of 306 patients), respectively. Septic shock with multiorgan failure was the cause of death in 56.6% of the deceased patients (n = 73) and acute respiratory distress syndrome in 35.3% (n = 47) patients. Of the deceased, 1 patient was less than 12 years old, 56.8% were between 13 and 64 years of age and 42.5% were geriatric, that is, 65 years of age or older. There were no comorbidities in 35.1% of the deceased patients. The cause of death did not vary with the age group. Conclusion: The in-hospital and intensive care unit mortality during the second wave was 9.3% and 37.6%, respectively. There was no major age group shift in the second wave as compared to the first wave. However, a significant number of patients (35.1%) did not have any comorbidity. Septic shock with multiorgan failure was the most common cause of death followed by acute respiratory distress syndrome.
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页码:24 / 29
页数:6
相关论文
共 9 条
[1]   Clinicoepidemiological Features and Mortality Analysis of Deceased Patients with COVID-19 in a Tertiary Care Centre [J].
Aggarwal, Richa ;
Bhatia, Ridhima ;
Kulshrestha, Kshitija ;
Soni, Kapil D. ;
Viswanath, Renjith ;
Singh, Ashutosh K. ;
Iyer, Karthik, V ;
Khanna, Puneet ;
Bhattacharjee, Sulagna ;
Patel, Nishant ;
Aravindan, Ajisha ;
Gupta, Anju ;
Singh, Yudhyavir ;
Ganesh, Venkata ;
Kumar, Rakesh ;
Ayub, Arshed ;
Kumar, Shailender ;
Prakash, Kellika ;
Venkateswaran, Vineeta ;
Bhoi, Debesh ;
Soneja, Manish ;
Mathur, Purva ;
Malhotra, Rajesh ;
Wig, Naveet ;
Guleria, Randeep ;
Trikha, Anjan .
INDIAN JOURNAL OF CRITICAL CARE MEDICINE, 2021, 25 (06) :622-628
[2]   Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. [J].
Brower, RG ;
Matthay, MA ;
Morris, A ;
Schoenfeld, D ;
Thompson, BT ;
Wheeler, A ;
Wiedemann, HP ;
Arroliga, AC ;
Fisher, CJ ;
Komara, JJ ;
Perez-Trepichio, P ;
Parsons, PE ;
Wolkin, R ;
Welsh, C ;
Fulkerson, WJ ;
MacIntyre, N ;
Mallatratt, L ;
Sebastian, M ;
McConnell, R ;
Wilcox, C ;
Govert, J ;
Thompson, D ;
Clemmer, T ;
Davis, R ;
Orme, J ;
Weaver, L ;
Grissom, C ;
Eskelson, M ;
Young, M ;
Gooder, V ;
McBride, K ;
Lawton, C ;
d'Hulst, J ;
Peerless, JR ;
Smith, C ;
Brownlee, J ;
Pluss, W ;
Kallet, R ;
Luce, JM ;
Gottlieb, J ;
Elmer, M ;
Girod, A ;
Park, P ;
Daniel, B ;
Gropper, M ;
Abraham, E ;
Piedalue, F ;
Glodowski, J ;
Lockrem, J ;
McIntyre, R .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (18) :1301-1308
[3]   Hospitalization and Critical Care of 109 Decedents with COVID-19 Pneumonia in Wuhan, China [J].
Du, Rong-Hui ;
Liu, Li-Min ;
Yin, Wen ;
Wang, Wen ;
Guan, Lu-Lu ;
Yuan, Ming-Li ;
Li, Yu-Lei ;
Hu, Yi ;
Li, Xu-Yan ;
Sun, Bing ;
Peng, Peng ;
Shi, Huan-Zhong .
ANNALS OF THE AMERICAN THORACIC SOCIETY, 2020, 17 (07) :839-846
[4]   An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome [J].
Fan, Eddy ;
Del Sorbo, Lorenzo ;
Goligher, Ewan C. ;
Hodgson, Carol L. ;
Munshi, Laveena ;
Walkey, Allan J. ;
Adhikari, Neill K. J. ;
Amato, Marcelo B. P. ;
Branson, Richard ;
Brower, Roy G. ;
Ferguson, Niall D. ;
Gajic, Ognjen ;
Gattinoni, Luciano ;
Hess, Dean ;
Mancebo, Jordi ;
Meade, Maureen O. ;
McAuley, Daniel F. ;
Pesenti, Antonio ;
Ranieri, V. Marco ;
Rubenfeld, Gordon D. ;
Rubin, Eileen ;
Seckel, Maureen ;
Slutsky, Arthur S. ;
Talmor, Daniel ;
Thompson, B. Taylor ;
Wunsch, Hannah ;
Uleryk, Elizabeth ;
Brozek, Jan ;
Brochard, Laurent J. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195 (09) :1253-1263
[5]  
Imam Z, 2020, J INTERN MED, V288, P469, DOI 10.1111/joim.13119
[6]   Second versus first wave of COVID-19 deaths: Shifts in age distribution and in nursing home fatalities [J].
Ioannidis, John P. A. ;
Axfors, Cathrine ;
Contopoulos-Ioannidis, Despina G. .
ENVIRONMENTAL RESEARCH, 2021, 195
[7]   COVID-19: consider cytokine storm syndromes and immunosuppression [J].
Mehta, Puja ;
McAuley, Daniel F. ;
Brown, Michael ;
Sanchez, Emilie ;
Tattersall, Rachel S. ;
Manson, Jessica J. .
LANCET, 2020, 395 (10229) :1033-1034
[8]   Clinical characteristics, laboratory outcome characteristics, comorbidities, and complications of related COVID-19 deceased: a systematic review and meta-analysis [J].
Qiu, Peishan ;
Zhou, Yunjiao ;
Wang, Fan ;
Wang, Haizhou ;
Zhang, Meng ;
Pan, Xingfei ;
Zhao, Qiu ;
Liu, Jing .
AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2020, 32 (09) :1869-1878
[9]   SARS-CoV-2 variants of concern are emerging in India [J].
Singh, Jasdeep ;
Rahman, Syed Asad ;
Ehtesham, Nasreen Z. ;
Hira, Subhash ;
Hasnain, Seyed E. .
NATURE MEDICINE, 2021, 27 (07) :1131-1133