Comprehensive multimodal management of borderline resectable pancreatic cancer: Current status and progress

被引：3
作者：
Wu, Hong-Yu [1 ]
Li, Jin-Wei [2 ]
Li, Jin-Zheng [1 ]
Zhai, Qi-Long [1 ]
Ye, Jing-Yuan [1 ]
Zheng, Si-Yuan [1 ]
Fang, Kun [3 ]
机构：
[1] Chongqing Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 2, Chongqing 400010, Peoples R China
[2] Guangxi Med Univ, Dept Neurosurg, Affiliated Hosp 4, Liuzhou 545000, Guangxi, Peoples R China
[3] Yinchuan Maternal & Child Hlth Hosp, Dept Surg, 56 Wenhua West Rd, Yinchuan 750000, Ningxia, Peoples R China
来源：
WORLD JOURNAL OF GASTROINTESTINAL SURGERY | 2023年 / 15卷 / 02期
关键词：
Borderline resectable pancreatic cancer; Neoadjuvant therapy; Resectability; Surgery; Multimodality treatment; Multidisciplinary teams; LONG-TERM OUTCOMES; PREOPERATIVE CHEMORADIATION THERAPY; INTERNATIONAL STUDY-GROUP; CT TEXTURE ANALYSIS; PHASE-II TRIAL; DUCTAL ADENOCARCINOMA; NEOADJUVANT THERAPY; RADIATION-THERAPY; CONSENSUS STATEMENT; VASCULAR RESECTION;
D O I：
10.4240/wjgs.v15.i2.142
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Borderline resectable pancreatic cancer (BRPC) is a complex clinical entity with specific biological features. Criteria for resectability need to be assessed in combination with tumor anatomy and oncology. Neoadjuvant therapy (NAT) for BRPC patients is associated with additional survival benefits. Research is currently focused on exploring the optimal NAT regimen and more reliable ways of assessing response to NAT. More attention to management standards during NAT, including biliary drainage and nutritional support, is needed. Surgery remains the cornerstone of BRPC treatment and multidisciplinary teams can help to evaluate whether patients are suitable for surgery and provide individualized management during the perioperative period, including NAT responsiveness and the selection of surgical timing.
引用
收藏
页码：142 / 162
页数：21
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