Metabolic Effects of Selected Conventional and Alternative Sweeteners: A Narrative Review

被引：6

作者：

Teysseire, Fabienne ^{[1
,2
]}

Bordier, Valentine ^{[1
,2
]}

Beglinger, Christoph ^{[2
]}

Woelnerhanssen, Bettina K. ^{[1
,2
]}

Meyer-Gerspach, Anne Christin ^{[1
,2
]}

机构：

[1] St Clara Res Ltd, St Claraspital, CH-4002 Basel, Switzerland

[2] Univ Basel, Fac Med, CH-4001 Basel, Switzerland

来源：

NUTRIENTS | 2024年 / 16卷 / 05期

基金：

瑞士国家科学基金会;

关键词：

glucose; fructose; sucrose; erythritol; xylitol; sucralose; D-allulose; sweeteners; satiation mechanisms; metabolic effects; DECREASES INSULIN SENSITIVITY; TERM DIETARY SUPPLEMENTATION; FRUCTOSE CORN SYRUP; ARTIFICIAL SWEETENER; CALORIE SWEETENERS; GLYCEMIC RESPONSES; HORMONE RESPONSE; ORAL INGESTION; BLOOD-GLUCOSE; URIC-ACID;

D O I：

10.3390/nu16050622

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Sugar consumption is known to be associated with a whole range of adverse health effects, including overweight status and type II diabetes mellitus. In 2015, the World Health Organization issued a guideline recommending the reduction of sugar intake. In this context, alternative sweeteners have gained interest as sugar substitutes to achieve this goal without loss of the sweet taste. This review aims to provide an overview of the scientific literature and establish a reference tool for selected conventional sweeteners (sucrose, glucose, and fructose) and alternative sweeteners (sucralose, xylitol, erythritol, and D-allulose), specifically focusing on their important metabolic effects. The results show that alternative sweeteners constitute a diverse group, and each substance exhibits one or more metabolic effects. Therefore, no sweetener can be considered to be inert. Additionally, xylitol, erythritol, and D-allulose seem promising as alternative sweeteners due to favorable metabolic outcomes. These alternative sweeteners replicate the benefits of sugars (e.g., sweetness and gastrointestinal hormone release) while circumventing the detrimental effects of these substances on human health.

引用

页数：18