Hearing Loss and Risk Factors in Very Low Birth Weight Infants

被引：4

作者：

Frezza, Simonetta ^{[1
]}

Tiberi, Eloisa ^{[1
]}

Corsello, Mirta ^{[1
]}

Priolo, Francesca ^{[1
]}

Cota, Francesco ^{[1
]}

Catenazzi, Piero ^{[2
]}

Conti, Guido ^{[3
]}

Costa, Simonetta ^{[1
]}

Vento, Giovanni ^{[1
]}

机构：

[1] Fdn Policlin Univ A Gemelli IRCCS, Catholic Univ Sacred Heart, Dept Woman & Child Hlth & Publ Hlth, I-00168 Rome, Italy

[2] Maggiore Hosp, Neonatal Intens Care Unit, I-40133 Bologna, Italy

[3] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli IRCCS, Dept Head & Neck Surg, Clin Otorhinolaryngol Audiol Serv, I-00168 Rome, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 24期

关键词：

very low birth weight infants; sensorineural hearing loss; neonatal screenings; ototoxic drugs; neonatal intensive care unit; NEONATAL INTENSIVE-CARE; PRETERM INFANTS; CHILDREN; INTERVENTION; PREMATURITY;

D O I：

10.3390/jcm12247583

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The incidence of sensorineural hearing loss (SNHL) is still high in very low birth weight (VLBW) infants. The purpose of our study was to provide the prevalence rates of SNHL and to analyze the risk factors of hearing impairment and changes in hearing thresholds in a cohort of VLBW infants. A retrospective observational study was conducted in our neonatal intensive care unit (NICU) from 2012 to 2016. All VLBW infants included were screened by transient evoked otoacoustic emissions (TEOAEs) and diagnostic auditory brainstem response (ABR). In total, we enrolled 316 infants and SNHL was diagnosed in 68, leading to an early incidence of 21.5% as 36 infants out of 68 improved. Finally, SNHL was confirmed in 20 patients (6.3%) who needed hearing aids. They were significantly smaller, sicker, had longer hospitalizations, and received more ototoxic therapies. Logistic regression analysis showed that gestational age (GA) influenced the association between drugs and SNHL. The results underlined how the total exposure to antibiotics is significantly associated with SNHL, even after GA correction. In conclusion, GA, birth weight and, above all, the length and complexity of NICU stay quantify the risk of SNHL and should be considered at the individual level for parent counseling.

引用

页数：12

共 36 条

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