Management of inflammatory bowel disease in the elderly: A review

被引:20
作者
Sousa, Paula [1 ]
Bertani, Lorenzo [2 ]
Rodrigues, Claudio [1 ]
机构
[1] Tondela Viseu Hosp Ctr, Dept Gastroenterol, Viseu Unit, P-3504509 Viseu, Portugal
[2] Pontedera Hosp, Dept Gen Surg & Gastroenterol, Tuscany North West ASL, Pontedera, Italy
关键词
Crohn's disease; Frailty; Ulcerative colitis; EVIDENCE-BASED CONSENSUS; ANTI-TNF THERAPY; TREATMENT-RELATED COMPLICATIONS; CROHNS-DISEASE; ULCERATIVE-COLITIS; INCREASED RISK; MAINTENANCE THERAPY; SERIOUS INFECTIONS; NATURAL-HISTORY; OLDER PATIENTS;
D O I
10.1016/j.dld.2022.12.024
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The burden of Inflammatory Bowel Disease (IBD) is increasing worldwide, with a particular increase in the prevalence in the elderly population, due to the ageing of young-onset IBD as well as to the increasing incidence in elderly patients.Elderly IBD patients present specific challenges to the treating physician, as they have comorbidities, lower functional reserves, and higher risk of treatment-related complications. The diagnosis of IBD in the elderly may be difficult due to a more subtle disease presentation and to a wide range of differential diagnosis. Moreover, as these patients are often excluded from clinical trials, there is a lack of high-quality evidence to inform on the most appropriate management.Despite an increasing prevalence, the management of IBD in the elderly is still hindered by frequent misconceptions by physicians treating these patients. Due to a erroneous notion of a milder disease course and fear of adverse events, elderly IBD-patients are managed with frequent and continuous use of steroids and undertreated with effective medical therapies.In this review, we describe the principles of management of IBD in the elderly, which is a topic of increasing importance to IBD clinics, that will have to progressively adapt to care for an ageing population.& COPY; 2023 The Author(s). Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )
引用
收藏
页码:1001 / 1009
页数:9
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