Ipsilateral preictal alpha rhythm attenuation (IPARA): An EEG sign of side of seizure onset in temporal lobe epilepsy

被引:0
作者
Rezazadeh, Arezoo [1 ,2 ,3 ]
Bui, Esther [2 ]
Wennberg, Richard A. [2 ]
机构
[1] Univ Ottawa, Dept Med, Ottawa, ON, Canada
[2] Univ Toronto, Dept Med, Toronto, ON, Canada
[3] Univ Ottawa, Ottawa Hosp, Dept Med, 1053 Carling Ave, Ottawa, ON K1Y 4E9, Canada
来源
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2023年 / 110卷
关键词
Alpha rhythm; EEG; Lateralization; Preictal; Seizure onset zone; Thalamus; UNILATERAL HIPPOCAMPAL SCLEROSIS; PULVINAR; SCALP; CONNECTIVITY; SURGERY; CORTEX;
D O I
10.1016/j.seizure.2023.07.001
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose: Identification of the seizure onset zone is critically important for outlining the surgical plan in the treatment of pharmacoresistant focal epilepsy. In patients with temporal lobe epilepsy (TLE), bilateral ictal scalp EEG changes frequently occur and can make lateralization of the seizure onset zone difficult. We investigated the incidence and clinical utility of unilateral preictal alpha rhythm attenuation as a lateralizing sign of seizure onset in TLE.Methods: Scalp EEG recordings of the seizures acquired during presurgical video-EEG monitoring of 57 consecutive patients with TLE were reviewed retrospectively. Included patients had interictal baseline recordings demonstrating symmetrical posterior alpha rhythm and seizures occurring during wakefulness.Results: We identified a total of 649 seizures in the 57 patients, of which 448 seizures in 53 patients fulfilled the inclusion criteria. Among the 53 included patients, 7 patients (13.2%) exhibited a distinct attenuation of the posterior alpha rhythm prior to the first ictal EEG changes, in 26 of 112 (23.2%) included seizures. Preictal alpha rhythm attenuation in these seizures was ipsilateral to the ultimately determined side of seizure onset (based on video-EEG or intracranial EEG findings) in 22 (84.6%) of these seizures and bilateral in 4 (15.4%), and occurred on average 5.9 & PLUSMN; 2.6 s prior to ictal EEG onsets.Conclusion: Our findings suggest that in some patients with TLE lateralized preictal attenuation of the posterior alpha rhythm may be a useful indicator of side of seizure onset, presumably due to early disruption of thalamotemporo-occipital network function, likely mediated through the thalamus.
引用
收藏
页码:194 / 202
页数:9
相关论文
共 33 条
  • [1] Epilepsy surgery in patients with bilateral temporal lobe seizures: A systematic review
    Aghakhani, Yahya
    Liu, Xiaorong
    Jette, Nathalie
    Wiebe, Samuel
    [J]. EPILEPSIA, 2014, 55 (12) : 1892 - 1901
  • [2] Lateralizing and localizing values of ictal onset recorded on the scalp:: Evidence from simultaneous recordings with intracranial foramen ovale electrodes
    Alarcón, G
    Kissani, N
    Dad, M
    Elwes, RDC
    Ekanayake, J
    Hennessy, MJ
    Koutroumanidis, M
    Binnie, CD
    Polkey, CE
    [J]. EPILEPSIA, 2001, 42 (11) : 1426 - 1437
  • [3] Clinical significance of bilateral epileptiform discharges in temporal lobe epilepsy
    Asadi-Pooya, Ali A.
    Farazdaghi, Mohsen
    Shahpari, Marzieh
    [J]. ACTA NEUROLOGICA SCANDINAVICA, 2021, 143 (06): : 608 - 613
  • [4] Thalamic structural connectivity in medial temporal lobe epilepsy
    Barron, Daniel S.
    Tandon, Nitin
    Lancaster, Jack L.
    Fox, Peter T.
    [J]. EPILEPSIA, 2014, 55 (06) : e50 - e55
  • [5] Pulvinar Associative role in cortical function and clinical correlations
    Benarroch, Eduardo E.
    [J]. NEUROLOGY, 2015, 84 (07) : 738 - 747
  • [6] Features of acute DWI abnormalities related to status epilepticus
    Chatzikonstantinou, Anastasios
    Gass, Achim
    Foerster, Alex
    Hennerici, Michael G.
    Szabo, Kristina
    [J]. EPILEPSY RESEARCH, 2011, 97 (1-2) : 45 - 51
  • [7] Bitemporal epilepsy: A specific anatomo-electro-clinical phenotype in the temporal lobe epilepsy spectrum
    Didato, Giuseppe
    Chiesa, Valentina
    Villani, Flavio
    Pelliccia, Veronica
    Deleo, Francesco
    Gozzo, Francesca
    Canevini, Maria Paola
    Mai, Roberto
    Spreafico, Roberto
    Cossu, Massimo
    Tassi, Laura
    [J]. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2015, 31 : 112 - 119
  • [8] Beamforming Seizures from the Temporal Lobe Using Magnetoencephalography
    Dominguez, Luis Garcia
    Tarazi, Apameh
    Valiante, Taufik
    Wennberg, Richard
    [J]. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2023, 50 (02) : 201 - 213
  • [9] Mesial temporal lobe epilepsy: What have we learned?
    Engel, J
    [J]. NEUROSCIENTIST, 2001, 7 (04) : 340 - 352
  • [10] Frequency of bitemporal independent interictal epileptiform discharges in temporal lobe epilepsy
    Ergene, E
    Shih, JJ
    Blum, DE
    So, NK
    [J]. EPILEPSIA, 2000, 41 (02) : 213 - 218