First pediatric B-acute lymphoblastic leukemia patient treated with anti-CD19 chimeric antigen receptor T-cell therapy: Long-term remission or early cure?

被引：1
作者：
Bouzianas, Dimitrios [1 ,3 ]
Bouziana, Stella [2 ]
机构：
[1] BReMeL Biopharmaceut & Regenerat Med Labs, Thessaloniki, Greece
[2] Kings Coll Hosp London, Dept Hematol, London, England
[3] BReMeL Biopharmaceut & Regenerat Med Labs, 4th Thermaikou str, Thessaloniki 55534, Greece
来源：
HUMAN VACCINES & IMMUNOTHERAPEUTICS | 2024年 / 20卷 / 01期
关键词：
CAR T-cells; tisagenlecleucel; B-acute lymphoblastic leukemia; immunotherapy; long-term remission; cure;
D O I：
10.1080/21645515.2024.2321678
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页数：4
相关论文
共 50 条
  • [21] Nanobody-based anti-CD22-chimeric antigen receptor T cell immunotherapy exhibits improved remission against B-cell acute lymphoblastic leukemia
    Zhang, Tingting
    Wang, Tian
    You, Fengtao
    Li, Zixuan
    Chen, Dan
    Zhang, Kailu
    Tian, Shuaiyu
    Sheng, Binjie
    Wu, Hai
    Jiang, Licui
    Ma, Renyuxue
    An, Gangli
    Meng, Huimin
    Yang, Lin
    [J]. TRANSPLANT IMMUNOLOGY, 2022, 71
  • [22] Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy for Relapsed or Refractory Large B-Cell Lymphoma: Practical Implications for the Community Oncologist
    Jacobson, Caron A.
    Farooq, Umar
    Ghobadi, Armin
    [J]. ONCOLOGIST, 2020, 25 (01) : E138 - E146
  • [23] What is the Role of Hematopoietic Cell Transplantation (HCT) for Pediatric Acute Lymphoblastic Leukemia (ALL) in the Age of Chimeric Antigen Receptor T-Cell (CART) Therapy?
    Taraseviciute, Agne
    Broglie, Larisa
    Phelan, Rachel
    Bhatt, Neel S.
    Becktell, Kerri
    Burke, Michael J.
    [J]. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2019, 41 (05) : 337 - 344
  • [24] Parameters of long-term response with CD28-based CD19 chimaeric antigen receptor-modified T cells in children and young adults with B-acute lymphoblastic leukaemia
    Jacoby, Elad
    Bielorai, Bella
    Hutt, Daphna
    Itzhaki, Orit
    Adam, Etai
    Bar, Diana
    Besser, Michal J.
    Toren, Amos
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2022, 197 (04) : 475 - 481
  • [25] Efficacy and Safety of Children With Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia After Anti-CD19 CAR T-Cell Therapy Without Bridging Transplantation
    Shang, Qianwen
    Xue, Lian
    Lu, Aidong
    Jia, Yueping
    Zuo, YingXi
    Zeng, Huimin
    Zhang, Leping
    [J]. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2024, 24 (06) : 392 - 399.e5
  • [26] How to train your T cell: genetically engineered chimeric antigen receptor T cells versus bispecific T-cell engagers to target CD19 in B acute lymphoblastic leukemia
    Ruella, Marco
    Gill, Saar
    [J]. EXPERT OPINION ON BIOLOGICAL THERAPY, 2015, 15 (06) : 761 - 766
  • [27] Maintenance therapy for early loss of B-cell aplasia after anti-CD19 CAR T-cell therapy
    Gabelli, Maria
    Oporto-Espuelas, Macarena
    Burridge, Saskia
    Chu, Jan
    Farish, Susan
    Hedges, Emma
    Ware, Kirsty
    Williams, Lindsey
    Young, Lindsey
    Alajangi, Rajesh
    Ancliff, Philip
    Bartram, Jack
    Bonney, Denise
    Chenchara, Lenka
    Chiesa, Robert
    Cugno, Chiara
    Hodby, Katharine
    Jalowiec, Katarzyna A.
    Lazareva, Arina
    Lucchini, Giovanna
    Mirci-Danicar, Oana C.
    Mullanfiroze, Khushnuma
    Pavasovic, Vesna
    Rao, Anupama
    Rao, Kanchan
    Riley, Lynne
    Samarasinghe, Sujith
    Shenton, Geoff
    Silva, Juliana
    Vora, Ajay
    Hough, Rachael
    Amrolia, Persis J.
    Ghorashian, Sara
    [J]. BLOOD ADVANCES, 2024, 8 (08) : 1959 - 1963
  • [28] Impact of pre-infusion disease burden on outcomes in pediatric relapsed/refractory B-cell lymphoblastic leukemia following anti-CD19 CAR T-cell therapy
    Shang, Qianwen
    Wang, Yu
    Lu, Aidong
    Jia, Yueping
    Zuo, Yingxi
    Zeng, Huimin
    Zhang, Leping
    [J]. LEUKEMIA & LYMPHOMA, 2025, 66 (01) : 54 - 63
  • [29] Chimeric Antigens Receptor T Cell Therapy Improve the Prognosis of Pediatric Acute Lymphoblastic Leukemia With Persistent/Recurrent Minimal Residual Disease in First Complete Remission
    Hu, Guan-hua
    Cheng, Yi-fei
    Zuo, Ying-xi
    Chang, Ying-jun
    Suo, Pan
    Wu, Jun
    Jia, Yue-ping
    Lu, Ai-dong
    Li, Ying-chun
    Wang, Yu
    Jiao, Shun-chang
    Zhang, Long-ji
    Zhao, Xiang-yu
    Yan, Chen-hua
    Xu, Lan-ping
    Zhang, Xiao-hui
    Liu, Kai-yan
    Zhang, Le-ping
    Huang, Xiao-jun
    [J]. FRONTIERS IN IMMUNOLOGY, 2022, 12
  • [30] Anti-CD19 Chimeric Antigen Receptor T Cell Therapy With Tisagenlecleucel for Secondary Central Nervous System Lymphoma: A Case Series
    Dhaliwal, Armaan
    Mann, Shivtaj
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (09)
12345