Biomaterials for Drug Delivery and Human Applications

被引:35
作者
Trucillo, Paolo [1 ]
机构
[1] Univ Naples Federico II, Dept Chem Mat & Ind Prod Engn, Piazzale V Tecchio 80, I-80125 Naples, Italy
关键词
biomaterials; drug-delivery systems; regenerative medicine; diagnostic tools; targeting; POLYETHYLENE-GLYCOL; TISSUE; NANOPARTICLES; POLYMERS; MEDICINE; SYSTEMS; RELEASE; CHALLENGES; CARTILAGE; ALGINATE;
D O I
10.3390/ma17020456
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Biomaterials embody a groundbreaking paradigm shift in the field of drug delivery and human applications. Their versatility and adaptability have not only enriched therapeutic outcomes but also significantly reduced the burden of adverse effects. This work serves as a comprehensive overview of biomaterials, with a particular emphasis on their pivotal role in drug delivery, classifying them in terms of their biobased, biodegradable, and biocompatible nature, and highlighting their characteristics and advantages. The examination also delves into the extensive array of applications for biomaterials in drug delivery, encompassing diverse medical fields such as cancer therapy, cardiovascular diseases, neurological disorders, and vaccination. This work also explores the actual challenges within this domain, including potential toxicity and the complexity of manufacturing processes. These challenges emphasize the necessity for thorough research and the continuous development of regulatory frameworks. The second aim of this review is to navigate through the compelling terrain of recent advances and prospects in biomaterials, envisioning a healthcare landscape where they empower precise, targeted, and personalized drug delivery. The potential for biomaterials to transform healthcare is staggering, as they promise treatments tailored to individual patient needs, offering hope for improved therapeutic efficacy, fewer side effects, and a brighter future for medical practice.
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收藏
页数:27
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