Diagnostic Utility of TUNEL Staining for Degenerative Keratoacanthoma Requiring Pathologic Differentiation from Seborrheic Keratosis

被引：1

作者：

Nakanishi, Mari ^{[1
]}

Kondo, Makoto ^{[1
]}

Habe, Koji ^{[1
]}

Hayashi, Akinobu ^{[2
]}

Yamanaka, Keiichi ^{[1
]}

机构：

[1] Mie Univ, Grad Sch Med, Dept Dermatol, Tsu, Japan

[2] Mie Univ, Grad Sch Med, Dept Oncol Pathol, Tsu, Japan

来源：

CASE REPORTS IN DERMATOLOGY | 2023年 / 15卷 / 01期

关键词：

Keratoacanthoma; Degenerative keratoacanthoma; Terminal deoxynucleotidyl transferase dUTP nick end labeling stain; Seborrheic keratosis; Immunological staining;

D O I：

10.1159/000529728

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Tumors developed in 2 old women presented with pathological findings similar to seborrheic keratosis, although the clinical feature of tumor showed typical keratoacanthoma. In addition to these two cases, we compared the pathological findings of a total of four cases, one case each of keratoacanthoma and seborrheic keratosis, which were clinically and histopathological typical. These two cases and the typical keratoacanthoma showed cell apoptosis by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining and infiltration of cytotoxic T cells. The keratoacanthoma in the decompensated stage may be histologically similar to seborrheic keratosis. TUNEL staining can help in the diagnosis of fading keratoacanthoma.

引用

页码：56 / 60

页数：5

共 6 条

[1]

Christine J., 2010, Clin Dermatol, V28, P254

[2] Keratoacanthoma: Clinical and histopathologic features of regression [J].