Non-invasive imaging biomarkers for liver steatosis in non-alcoholic fatty liver disease: present and future

被引：16

作者：

Nogami, Asako ^{[1
]}

Yoneda, Masato ^{[1
]}

Iwaki, Michihiro ^{[1
]}

Kobayashi, Takashi ^{[1
]}

Honda, Yasushi ^{[1
]}

Ogawa, Yuji ^{[1
,2
]}

Imajo, Kento ^{[1
,3
]}

Saito, Satoru ^{[1
]}

Nakajima, Atsushi ^{[1
]}

机构：

[1] Yokohama City Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, Sch Med, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan

[2] Natl Hosp Org Yokohama Med Ctr, Dept Gastroenterol, Yokohama, Kanagawa, Japan

[3] Shinyurigaoka Gen Hosp, Dept Gastroenterol & Endoscopy, Kawasaki, Kanagawa, Japan

来源：

CLINICAL AND MOLECULAR HEPATOLOGY | 2023年 / 29卷

关键词：

Non-alcoholic fatty liver disease; Liver steatosis; Biomarker; Ultrasonography; CLINICAL-PRACTICE GUIDELINES; CONTROLLED ATTENUATION PARAMETER; MAGNETIC-RESONANCE-SPECTROSCOPY; DUAL-ENERGY CT; HEPATIC STEATOSIS; TRANSIENT ELASTOGRAPHY; HISTOLOGIC FEATURES; COMPUTED-TOMOGRAPHY; DIAGNOSTIC-ACCURACY; FIBROSIS STAGE;

D O I：

10.3350/cmh.2022.0357

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Non-alcoholic fatty liver disease is currently the most common chronic liver disease, affecting up to 25% of the global population. Simple fatty liver, in which fat is deposited in the liver without fibrosis, has been regarded as a benign disease in the past, but it is now known to be prognostic. In the future, more emphasis should be placed on the quantification of liver fat. Traditionally, fatty liver has been assessed by histological evaluation, which requires an invasive examination; however, technological innovations have made it possible to evaluate fatty liver by non-invasive imaging methods, such as ultrasonography, computed tomography, and magnetic resonance imaging. In addition, quantitative as well as qualitative measurements for the detection of fatty liver have become available. In this review, we summarize the currently used qualitative evaluations of fatty liver and discuss quantitative evaluations that are expected to further develop in the future.

引用

收藏

页码：S123 / S135

页数：13

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