Risk factors of vestibular migraine-related brain white matter lesions

被引:2
|
作者
Shen, Yu [1 ,2 ]
Li, Defu [3 ]
Cao, Qian [1 ]
Hu, Mengyao [4 ]
Hou, Zhou [1 ]
Xu, Lijun [1 ]
Li, Yanping [1 ]
Hong, Daojun [2 ]
机构
[1] Nanchang Univ, Dept Neurol, Affiliated Hosp 2, Nanchang, Jiangxi, Peoples R China
[2] Nanchang Univ, Dept Neurol, Affiliated Hosp 1, Yong Wai Zheng St 17, Nanchang, Jiangxi, Peoples R China
[3] Nanchang Univ, Sch Publ Hlth, Jiangxi Prov Key Lab Prevent Med, Nanchang, Jiangxi, Peoples R China
[4] Nanchang Univ, Med Imaging Ctr, Affiliated Hosp 2, Nanchang, Jiangxi, Peoples R China
关键词
Vestibular migraine (VM); White matter lesions (WMLs); Risk factors; Clinical manifestations; HYPERINTENSITIES; LEUKOARAIOSIS; PROGRESSION; POPULATION; PREVALENCE; VERTIGO;
D O I
10.1007/s13760-022-02076-y
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective and purpose Migraine is related to white matter lesions (WMLs), and attack frequency and duration in migraine patients are thought to increase WMLs. However, the relationship between vestibular migraine (VM) and WMLs remains unclear. This study explored the risk factors for WMLs in VM patients and provided a basis for the prevention of WMLs in VM patients. Methods A large single-center cross-sectional study of patients with VM was conducted. None of the patients had comorbidities, such as hypertension and diabetes, or adverse lifestyle habits (smoking and drinking). All patients were divided into WML + and WML- groups after assessment of WMLs using magnetic resonance imaging (MRI). After collecting the patient's detailed medical history, statistical analysis was performed. Results In univariate analysis, the frequency of vertigo was statistically significant between the WML + and WML- groups. However, there was no significant difference in other clinical features. Multivariate regression analysis found that the frequency of vertigo (OR 2.399; 95% CI 1.014-5.679; p = 0.046) was an independent risk factor for WMLs. High frequency of vertigo episodes showed more pronounced risk factors (OR 9.607; 95% CI 1.061-87.014; p = 0.044). Conclusion These results substantiate that vertigo frequency is an independent risk factor for WMLs in VM. A high frequency of vertigo episodes is more likely to be associated with WMLs than a low frequency. These results suggest a possible approach to the prevention of WMLs in VM patients.
引用
收藏
页码:1833 / 1839
页数:7
相关论文
共 50 条
  • [11] The presence of brain white matter lesions in relation to preeclampsia and migraine
    Postma, I. R.
    van Oosterhout, W. P. J.
    de Groot, J. C.
    Terwindt, G. M.
    Zeeman, G. G.
    CEPHALALGIA, 2016, 36 (03) : 284 - 288
  • [12] Brain white matter lesions in migraine: what's the meaning?
    Colombo, Bruno
    Libera, D. Dalla
    Comi, G.
    NEUROLOGICAL SCIENCES, 2011, 32 : S37 - S40
  • [13] Brain white matter lesions in migraine: what’s the meaning?
    Bruno Colombo
    D. Dalla Libera
    G. Comi
    Neurological Sciences, 2011, 32 : 37 - 40
  • [14] Migraine-Related Gray Matter and White Matter Changes at a 1-Year Follow-Up Evaluation
    Liu, Jixin
    Lan, Lei
    Li, Guoying
    Yan, Xuemei
    Nan, Jiaofen
    Xiong, Shiwei
    Yin, Qing
    von Deneen, Karen M.
    Gong, Qiyong
    Liang, Fanrong
    Qin, Wei
    Tian, Jie
    JOURNAL OF PAIN, 2013, 14 (12): : 1703 - 1708
  • [15] Risk factors for ischemic white matter lesions
    Pavlovic, D. M.
    Pavlovic, A. M.
    Pekmezovic, T.
    Zidverc-Trajkovic, J.
    Jovanovic, Z.
    Mijajlovic, M.
    Tomic, G.
    Radojicic, A.
    Sternic, N.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 283 (1-2) : 308 - 308
  • [16] Changes of Migraine-Related White Matter Hyperintensities After 3 Years: A Longitudinal MRI Study
    Erdelyi-Botor, Szilvia
    Aradi, Mihaly
    Kamson, David Olayinka
    Kovacs, Norbert
    Perlaki, Gabor
    Orsi, Gergely
    Nagy, Szilvia Anett
    Schwarcz, Attila
    Doczi, Tamas
    Komoly, Samuel
    Deli, Gabriella
    Trauninger, Anita
    Pfund, Zoltan
    HEADACHE, 2015, 55 (01): : 55 - 70
  • [17] Risk factors of white matter hyperintensities in migraine patients
    Al-Hashel, J.
    HEADACHE, 2022, 62 (07): : 915 - 915
  • [18] Risk factors of white matter hyperintensities in migraine patients
    Al-Hashel, Jasem Yousef
    Alroughani, Raed
    Gad, Khaled
    Al-Sarraf, Lamiaa
    Ahmed, Samar Farouk
    BMC NEUROLOGY, 2022, 22 (01)
  • [19] Risk factors of white matter hyperintensities in migraine patients
    Jasem Yousef Al-Hashel
    Raed Alroughani
    Khaled Gad
    Lamiaa Al-Sarraf
    Samar Farouk Ahmed
    BMC Neurology, 22