The Role of Adipokines in Health and Disease

被引：199
作者：
Clemente-Suarez, Vicente Javier [1 ]
Redondo-Florez, Laura [2 ]
Beltran-Velasco, Ana Isabel [3 ]
Martin-Rodriguez, Alexandra [1 ]
Martinez-Guardado, Ismael [4 ]
Navarro-Jimenez, Eduardo [5 ]
Laborde-Cardenas, Carmen Cecilia [6 ]
Tornero-Aguilera, Jose Francisco [1 ]
机构：
[1] Univ Europea Madrid, Fac Sports Sci, Tajo St S-N, Madrid 28670, Spain
[2] Univ Europea Madrid, Fac Biomed & Hlth Sci, Dept Hlth Sci, C Tajo S-N, Madrid 28670, Spain
[3] Univ Nebrija, Fac Life & Nat Sci, Dept Psychol, Madrid 28248, Spain
[4] Univ Nebrija, Fac Life & Nat Sci, Dept Psychol, BRABE Grp, Madrid 28248, Spain
[5] Univ Simon Bolivar, Fac Ciencias Salud, Barranquilla 080002, Colombia
[6] Univ Simon Bolivar, Vicerrectoria Invest Innovac, Barranquilla 080005, Colombia
来源：
BIOMEDICINES | 2023年 / 11卷 / 05期
关键词：
adipokines; inflammation; cardiovascular disease; atherosclerosis disease; mental disease; eating behavior; metabolic disease; cancer; microbiota; nutrition; physical activity; CORONARY-ARTERY-DISEASE; LIFE-STYLE MODIFICATION; WHITE ADIPOSE-TISSUE; PLASMA LEPTIN LEVELS; DIET-INDUCED OBESITY; C-REACTIVE PROTEIN; GUT MICROBIOTA; METABOLIC SYNDROME; ENDOTHELIAL DYSFUNCTION; CARDIOVASCULAR-DISEASE;
D O I：
10.3390/biomedicines11051290
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a low-grade state of inflammation and different pathologies. The present review aims to analyze the role of adipokines in health and disease in order to understand the important functions and effects of these cytokines. For this aim, the present review delves into the type of adipocytes and the cytokines produced, as well as their functions; the relations of adipokines in inflammation and different diseases such as cardiovascular, atherosclerosis, mental diseases, metabolic disorders, cancer, and eating behaviors; and finally, the role of microbiota, nutrition, and physical activity in adipokines is discussed. This information would allow for a better understanding of these important cytokines and their effects on body organisms.
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页数：41
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