Stimuli-responsive switchable MRI nanoprobe for tumor theranostics

被引：25
作者：
Chen, Baode [1 ]
Liu, Liuhui [1 ]
Yue, Renye [1 ]
Dong, Zhe [1 ]
Lu, Chang [1 ]
Zhang, Cheng [1 ]
Guan, Guoqiang [1 ]
Liu, Huiyi [1 ]
Zhang, Qingpeng [1 ]
Song, Guosheng [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China
来源：
NANO TODAY | 2023年 / 51卷
关键词：
MRI probe; Stimuli-responsive; Switchable; Diagnosis and treatment; IRON-OXIDE NANOPARTICLES; MAGNETIC-RESONANCE; IN-VIVO; PHOTODYNAMIC THERAPY; CANCER-DIAGNOSIS; CONTRAST AGENTS; MICROENVIRONMENT; T-1; NANOPLATFORM; OXYGEN;
D O I：
10.1016/j.nantod.2023.101931
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
With the advancement in magnetic resonance imaging (MRI) technology, traditional single T1 or T2 contrast agents struggle to meet the demend for accuracy imaging. In comparison, novel dual-mode contrast agents that possess T1-T2 ability, have the potential to provide excellent imaging applications, due to their cap-ability of self-confirmation and cross-validation of MRI signal, ultimately resulting in improved accuracy of MRI imaging. Unlike traditional MRI contrast agents, which yield constant signal, causing excessive back-ground noise, responsive MRI probes are designed to provide signals that change in response to stimuli. The use of stimuli-activated MRI probes combined with switchable T1-T2 MRI can lead to highly selective and excellent contrast effects for MRI contrast agents. This review focuses on the responsive and switchable MRI probe types, highlights the mechanism of MRI signal transformation, evaluates their application in tumor imaging or therapies, and provides a brief prediction of the future development tendencies and challenges associated with switchable MRI probes.& COPY; 2023 Published by Elsevier Ltd.
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页数：25
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共 159 条
  • [81] Simultaneously activating highly selective ratiometric MRI and synergistic therapy in response to intratumoral oxidability and acidity[J]. Liu, Yuxin;Jia, Qi;Guo, Quanwei;Wei, Wei;Zhou, Jing. BIOMATERIALS, 2018
  • [82] Redox chemistry-enabled stepwise surface dual nanoparticle engineering of 2D MXenes for tumor-sensitive T1 and T2 MRI-guided photonic breast-cancer hyperthermia in the NIR-II biowindow[J]. Liu, Zhuang;Zhao, Menglong;Yu, Luodan;Peng, Weijun;Chen, Yu;Zhang, Shengjian. BIOMATERIALS SCIENCE, 2022(06)
  • [83] Light-free Generation of Singlet Oxygen through Manganese-Thiophene Nanosystems for pH-Responsive Chemiluminescence Imaging and Tumor Therapy[J]. Lu, Chang;Zhang, Cheng;Wang, Peng;Zhao, Yan;Yang, Yue;Wang, Youjuan;Yuan, Haifeng;Qu, Shuanglin;Zhang, Xiaobing;Song, Guosheng;Pu, Kanyi. CHEM, 2020(09)
  • [84] Highly Sensitive Diagnosis of Small Hepatocellular Carcinoma Using pH-Responsive Iron Oxide Nanocluster Assemblies[J]. Lu, Jingxiong;Sun, Jihong;Li, Fangyuan;Wang, Jin;Liu, Jianan;Kim, Dokyoon;Fan, Chunhai;Hyeon, Taeghwan;Ling, Daishun. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018(32)
  • [85] CuFeSe2-based thermo-responsive multifunctional nanomaterial initiated by a single NIR light for hypoxic cancer therapy[J]. Lu, Juan;Yang, Jun;Yang, Dan;Hu, Shanshan;Sun, Qianqian;Yang, Guixin;Gai, Shili;Wang, Zhao;Yang, Piaoping. JOURNAL OF MATERIALS CHEMISTRY B, 2021(02)
  • [86] Nanoscale Metal-Organic Framework for Highly Effective Photodynamic Therapy of Resistant Head and Neck Cancer[J]. Lu, Kuangda;He, Chunbai;Lin, Wenbin. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014(48)
  • [87] A tumor microenvironment dual responsive contrast agent for contrary contrast-magnetic resonance imaging and specific chemotherapy of tumors[J]. Lu, Yudie;Feng, Jie;Liang, Zhiyu;Lu, Xuanyi;Guo, Shuai;Huang, Lin;Xiong, Wei;Chen, Sijin;Zhou, Huimin;Ma, Xuehua;Xu, Yikai;Qiu, Xiaozhong;Wu, Aiguo;Chen, Xiaoyuan;Shen, Zheyu. NANOSCALE HORIZONS, 2022(04)
  • [88] Lu Z., 2023, ACS APPL NANO MATER, V6, P119
  • [89] Multifunctional Nanosnowflakes for T1-T2 Double-Contrast Enhanced MRI and PAI Guided Oxygen Self-Supplementing Effective Anti-Tumor Therapy[J]. Lv, Yijie;Kan, Junnan;Luo, Mingfang;Yang, Changfeng;Luo, Xunrong;Lin, Xiaoqian;Li, Hao;Li, Xueming;Li, Yuping;Yang, Caixia;Liu, Yan;Li, Xianglin. INTERNATIONAL JOURNAL OF NANOMEDICINE, 2022
  • [90] Redox-Sensitive Clustered Ultrasmall Iron Oxide Nanoparticles for Switchable T2/T1-Weighted Magnetic Resonance Imaging Applications[J]. Ma, Dan;Shi, Menghan;Li, Xin;Zhang, Jiulong;Fan, Yu;Sun, Kai;Jiang, Tingting;Peng, Chen;Shi, Xiangyang. BIOCONJUGATE CHEMISTRY, 2020(02)
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