Syntheses, crystal structures and Hirshfeld surface analysis of 2-(benzylsulfanyl)-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole and 2-[(2-chloro-6-fluorobenzyl)sulfanyl]-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole

被引：3

作者：

Okmanov, Rasul Ya. ^{[1
,2
]}

Ziyaev, Abdukhakim A. ^{[1
]}

Abdukarimov, Azimboy Sh. ^{[2
]}

Toshmurodov, Turdibek T. ^{[1
]}

Kholikov, Tursunali S. ^{[2
]}

机构：

[1] Acad Sci Uzbek, S Yunusov Inst Chem Plant Subst, Mirzo Ulugbek Str 77, Tashkent 100170, Uzbekistan

[2] Natl Univ Uzbekistan, Univ Str 4, Tashkent 100174, Uzbekistan

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2023年 / 79卷

关键词：

synthesis; 1,3,4-oxadiazole; crystal structure; Hirshfeld surface analysis; QUANTITATIVE-ANALYSIS;

D O I：

10.1107/S2056989023004164

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compounds were synthesized by alkylation of 5-[(4-dimethylamino)phenyl]-1,3,4-oxadiazole-2-thiol with benzyl chloride or 2-chloro-6-fluorobenzyl chloride in the presence of potassium carbonate. The yields of 2-(benzylsulfanyl)-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole, C17H17N3OS (I), and 2-[(2-chloro-6-fluorobenzyl)sulfanyl]-5-[4-(dimethylamino)phenyl]-1,3,4-oxadiazole, C17H15ClFN3OS (II), were 96 and 92%, respectively. In the crystal structures of (I) and (II), C-H center dot center dot center dot pi interactions are observed between neighboring molecules. Hirshfeld surface analysis indicates that H center dot center dot center dot H and H center dot center dot center dot C/C center dot center dot center dot H interactions make the most important contributions to the crystal packing.

引用

页码：552 / +

页数：14

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