Primary lung cancer with pulmonary alveolar proteinosis treated with immune checkpoint inhibitor: A case report

被引：1

作者：

Horie, Mika ^{[1
]}

Nakashima, Kazuhisa ^{[1
]}

Amano, Yoshihiro ^{[1
]}

Shiratsuki, Yohei ^{[1
]}

Murakami, Kotaro ^{[1
]}

Isobe, Takeshi ^{[1
]}

Tsubata, Yukari ^{[1
]}

机构：

[1] Shimane Univ, Fac Med, Dept Internal Med, Div Med Oncol & Resp Med, 89-1 Enya Cho, Izumo, Shimane 6938501, Japan

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2024年 / 47卷

关键词：

Pulmonary alveolar proteinosis; Lung cancer; Immune checkpoint inhibitor; Atezolizumab; Case report; CHEMOTHERAPY; PATIENT;

D O I：

10.1016/j.rmcr.2023.101976

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Primary lung cancer with pulmonary alveolar proteinosis (PAP) is a rare condition. We present a case of a patient with primary lung cancer with PAP treated with an immune checkpoint inhibitor (ICI). A 62-year-old man was diagnosed with autoimmune PAP 8 years prior to current admission. Lung adenocarcinoma was found in his right lung, and platinum-based chemotherapy was administered, followed by atezolizumab. He experienced disease progression after atezolizumab treatment, whereas ICI-induced pneumonia or exacerbation of PAP did not occur. This indicates that ICI may be safely used in patients with primary lung cancer with PAP.

引用

页数：3

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