The 2022 West Nile Virus Season in Greece; A Quite Intense Season

被引：15

作者：

Pervanidou, Danai ^{[1
]}

Kefaloudi, Chrysovaladou Niki ^{[1
]}

Vakali, Anna ^{[1
]}

Tsakalidou, Ourania ^{[2
]}

Karatheodorou, Myrsini ^{[2
]}

Tsioka, Katerina ^{[2
]}

Evangelidou, Maria ^{[3
]}

Mellou, Kassiani ^{[1
]}

Pappa, Styliani ^{[2
]}

Stoikou, Konstantina ^{[2
]}

Bakaloudi, Vasiliki ^{[4
]}

Koliopoulos, George ^{[5
]}

Stamoulis, Kostas ^{[6
]}

Patsoula, Eleni ^{[7
]}

Politis, Constantina ^{[1
]}

Hadjichristodoulou, Christos ^{[8
]}

Papa, Anna ^{[2
]}

机构：

[1] Natl Publ Hlth Org EODY, Athens 15123, Greece

[2] Aristotle Univ Thessaloniki, Fac Hlth Sci, Natl Reference Ctr Arboviruses & Haemorrhag Fever, Med Sch,Dept Microbiol, Thessaloniki 54124, Greece

[3] Hellenic Pasteur Inst, Athens 11521, Greece

[4] AHEPA Univ Gen Hosp, Mol Blood Ctr, Thessaloniki 54636, Greece

[5] Agr Univ Athens, Sch Plant Sci, Dept Crop Sci, Athens 11855, Greece

[6] Hellen Natl Blood Transfus Ctr, Athens 13672, Greece

[7] Univ West Attica, Sch Publ Hlth, Dept Publ Hlth Policy, Athens 11521, Greece

[8] Univ Thessaly, Sch Hlth Sci, Fac Med, Dept Hyg & Epidemiol, Thessalia 41222, Greece

来源：

VIRUSES-BASEL | 2023年 / 15卷 / 07期

关键词：

West Nile virus; Greece; mosquito-borne disease; vector-borne disease; LINEAGE; 2; PHYLOGENETIC ANALYSIS; CENTRAL MACEDONIA; CULEX MOSQUITOS; TRANSMISSION; INFECTION; OUTBREAK; EUROPE; EPIDEMIOLOGY; EMERGENCE;

D O I：

10.3390/v15071481

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Since 2010, the West Nile virus (WNV) has been established in Greece. We describe the epidemiology of diagnosed human WNV infections in Greece with a focus on the 2022 season. During the transmission period, clinicians were sending samples from suspected cases for testing. Active laboratory-based surveillance was performed with immediate notification of diagnosed cases. We collected clinical information and interviewed patients on a timely basis to identify their place of exposure. Besides serological and molecular diagnostic methods, next-generation sequencing was also performed. In 2022, 286 cases of WNV infection were diagnosed, including 278 symptomatic cases and 184 (64%) cases with neuroinvasive disease (WNND); 33 patients died. This was the third most intense season concerning the number of WNND cases, following 2018 and 2010. Most (96%) cases were recorded in two regions, in northern and central Greece. The virus strain was a variant of previous years, clustering into the Central European subclade of WNV lineage 2. The 2022 WNV season was quite intense in Greece. The prompt diagnosis and investigation of cases are considered pivotal for the timely response, while the availability of whole genome sequences enables studies on the molecular epidemiology of the disease.

引用

页数：15

共 63 条

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