From NAFLD to HCC: Advances in noninvasive diagnosis

被引：10

作者：

Xu, Qinchen ^{[1
]}

Feng, Maoxiao ^{[2
]}

Ren, Yidan ^{[1
]}

Liu, Xiaoyan ^{[2
]}

Gao, Huiru ^{[1
]}

Li, Zigan ^{[1
]}

Su, Xin ^{[1
]}

Wang, Qin ^{[3
]}

Wang, Yunshan ^{[2
]}

机构：

[1] Shandong Univ, Hosp 2, Cheeloo Coll Med, Dept Clin Lab, Jinan 250033, Shandong, Peoples R China

[2] Shandong First Med Univ, Dept Clin Lab, Shandong Prov Hosp, Jinan 250021, Shandong, Peoples R China

[3] Shandong Univ, Qilu Hosp, Dept Anesthesiol, 107 Wenhua Xi Rd, Jinan 250012, Peoples R China

来源：

BIOMEDICINE & PHARMACOTHERAPY | 2023年 / 165卷

基金：

中国国家自然科学基金;

关键词：

NAFLD; NASH; Fibrosis; HCC; Noninvasive diagnosis; NONALCOHOLIC FATTY LIVER; LONG-TERM OUTCOMES; HEPATOCELLULAR-CARCINOMA; FIBROSIS PROGRESSION; RISK-FACTORS; DISEASE; STEATOHEPATITIS; STEATOSIS; BIOMARKER; PREDICTS;

D O I：

10.1016/j.biopha.2023.115028

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Non-alcoholic fatty liver disease (NAFLD) has gradually become one of the major liver health problems in the world. The dynamic course of the disease goes through steatosis, inflammation, fibrosis, and carcinoma. Before progressing to carcinoma, timely and effective intervention will make the condition better, which highlights the importance of early diagnosis. With the further study of the biological mechanism in the pathogenesis and progression of NAFLD, some potential biomarkers have been discovered, and the possibility of their clinical application is gradually being discussed. At the same time, the progress of imaging technology and the emergence of new materials and methods also provide more possibilities for the diagnosis of NAFLD. This article reviews the diagnostic markers and advanced diagnostic methods of NAFLD in recent years.

引用

页数：15

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