Managing Atopic Dermatitis in Patients With Skin of Color

被引:10
作者
Davis, Carla M. [1 ,6 ]
Flohr, Carsten [2 ,3 ]
Gupta, Meera R. [1 ]
Koplin, Jennifer J. [4 ,5 ]
机构
[1] Texas Childrens Hosp, Baylor Coll Med, Dept Pediat, Div Immunol Allergy & Retrovirol, Houston, TX USA
[2] St Johns Inst Dermatol, Kings Coll London, London, England
[3] Guys & St Thomas NHS Fdn Trust, London, England
[4] Univ Queensland, Child Hlth Res Ctr, Brisbane, Qld, Australia
[5] Murdoch Childrens Res Inst, Parkville, Vic, Australia
[6] Texas Childrens Hosp, Baylor Coll Med, Dept Pediat, Div Immunol Allergy & Retrovirol, 1102 Bates Ave,MC 330, Houston, TX 77030 USA
关键词
Atopic dermatitis; Skin of color; Diagnosis; Treatment; Prevalence; Management; DISEASE SEVERITY; UNITED-STATES; PART I; RISK; CARE; PREVALENCE; CHILDREN; ECZEMA; HYPERPIGMENTATION; COLONIZATION;
D O I
10.1016/j.jaip.2023.03.041
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Managing atopic dermatitis (AD) in patients with skin of color presents unique challenges for the clinician. There is increasing evidence that AD has higher prevalence, persistence, and severity among skin of color populations. This is likely to be partly related to differences in living conditions and exposure to irritants and allergens, among other factors. Assessment of AD severity in patients with darker skin can be challenging, in particular the assessment of erythema, leading to the potential for underscoring AD severity. Variations in disease have also been described, with the potential for a greater risk of inflammation-induced nodularity and hyper-or hypo -pigmentation. Management challenges include variable adher-ence to treatment, potential disparities in access to health care, and differences in the metabolism of cyclosporine. Optimal management of AD in patients with skin of color requires a tailored approach. Here, we review approaches to diagnosing AD, evaluating extent and severity with subjective and objective measures, considering treatment options for patients with skin of color, and highlighting areas for improvement in AD care for skin of color populations. (c) 2023 American Academy of Al-lergy, Asthma & Immunology
引用
收藏
页码:1376 / 1383
页数:8
相关论文
共 57 条
[1]   Genetic ancestry does not explain increased atopic dermatitis susceptibility or worse disease control among African American subjects in 2 large US cohorts [J].
Abuabara, Katrina ;
You, Yue ;
Margolis, David J. ;
Hoffmann, Thomas J. ;
Risch, Neil ;
Jorgenson, Eric .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2020, 145 (01) :192-+
[2]   The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group [J].
Alexander, H. ;
Paller, A. S. ;
Traidl-Hoffmann, C. ;
Beck, L. A. ;
De Benedetto, A. ;
Dhar, S. ;
Girolomoni, G. ;
Irvine, A. D. ;
Spuls, P. ;
Su, J. ;
Thyssen, J. P. ;
Vestergaard, C. ;
Werfel, T. ;
Wollenberg, A. ;
Deleuran, M. ;
Flohr, C. .
BRITISH JOURNAL OF DERMATOLOGY, 2020, 182 (06) :1331-1342
[3]   Insights in Skin of Color Patients With Atopic Dermatitis and the Role of Skincare in Improving Outcomes [J].
Alexis, Andrew ;
Woolery-Lloyd, Heather ;
Andriessen, Anneke ;
Callender, Valerie ;
Gonzalez, Mercedes ;
Heath, Candrice ;
Han, George .
JOURNAL OF DRUGS IN DERMATOLOGY, 2022, 21 (05) :462-470
[4]   Assessment and Monitoring Challenges Among Patients With Moderate-to-Severe Atopic Dermatitis Across Fitzpatrick Skin Types: A Photographic Review and Case Series [J].
Aoki, Valeria ;
Oliveira, Marilia ;
Wegzyn, Colleen ;
Desai, Seemal R. ;
Jewell, Susan ;
Ladizinski, Barry ;
Simpson, Eric L. .
DERMATITIS, 2022, 33 (6S) :S24-S36
[5]  
atopicdermatitisatlas, Global Report on Atopic Dermatitis
[6]   Racial differences in atopic dermatitis [J].
Brunner, Patrick M. ;
Guttman-Yassky, Emma .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2019, 122 (05) :449-455
[7]   The Eumelanin Human Skin Colour Scale: a proof-of-concept study [J].
Dadzie, Ophelia E. ;
Sturm, Rick A. ;
Fajuyigbe, Damilola ;
Petit, Antoine ;
Jablonski, Nina G. .
BRITISH JOURNAL OF DERMATOLOGY, 2022, 187 (01) :99-104
[8]   Health disparities in allergic and immunologic conditions in racial and ethnic underserved populations: A Work Group Report of the AAAAI Committee on the Underserved [J].
Davis, Carla M. ;
Apter, Andrea J. ;
Casillas, Adrian ;
Foggs, Michael B. ;
Louisias, Margee ;
Morris, Elsie C. ;
Nanda, Anil ;
Nelson, Michael R. ;
Ogbogu, Princess U. ;
Walker-McGill, Cheryl Lynn ;
Wang, Julie ;
Perry, Tamara T. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2021, 147 (05) :1579-1593
[9]   Patterns and trends in eczema management in UK primary care (2009-2018): A population-based cohort study [J].
de Lusignan, Simon ;
Alexander, Helen ;
Broderick, Conor ;
Dennis, John ;
McGovern, Andrew ;
Feeney, Clarie ;
Flohr, Carsten .
CLINICAL AND EXPERIMENTAL ALLERGY, 2021, 51 (03) :483-494
[10]   The epidemiology of eczema in children and adults in England: A population-based study using primary care data [J].
de Lusignan, Simon ;
Alexander, Helen ;
Broderick, Conor ;
Dennis, John ;
McGovern, Andrew ;
Feeney, Claire ;
Flohr, Carsten .
CLINICAL AND EXPERIMENTAL ALLERGY, 2021, 51 (03) :471-482