Mortality Associated With Occupational Exposure in Helsinki, Finland-A 24-Year Follow-up

被引:1
作者
Jalasto, Juuso [1 ,2 ]
Luukkonen, Ritva [3 ]
Lindqvist, Ari [4 ,5 ]
Langhammer, Arnulf [6 ,7 ]
Kankaanranta, Hannu [8 ,9 ,10 ]
Backman, Helena [11 ]
Ronmark, Eva [11 ]
Sovijarvi, Anssi [1 ,2 ]
Kauppi, Paula [4 ,5 ]
Piirila, Paivi [1 ,2 ]
机构
[1] Helsinki Univ Cent Hosp, HUS Med Diagnost Ctr, Dept Clin Physiol, PL 281, Helsinki 00029, Finland
[2] Univ Helsinki, PL 281, Helsinki 00029, Finland
[3] Finnish Inst Occupat Hlth, Helsinki, Finland
[4] Helsinki Univ Hosp, Heart & Lung Ctr, Dept Pulm Med, Helsinki, Finland
[5] Univ Helsinki, Helsinki, Finland
[6] Norwegian Univ Sci & Technol, HUNT Res Ctr, Dept Publ Hlth & Nursing, NTNU, Levanger, Norway
[7] Nord Trondelag Hosp Trust, Levanger Hosp, Levanger, Norway
[8] Univ Gothenburg, Inst Med, Krefting Res Ctr, Dept Internal Med & Clin Nutr, Gothenburg, Sweden
[9] Seinajoki Cent Hosp, Dept Resp Med, Seinajoki, Finland
[10] Tampere Univ, Fac Med & Hlth Technol, Resp Res Grp, Tampere, Finland
[11] Umea Univ, Dept Publ Hlth & Clin Med, OLIN Unit, Sect Sustainable Hlth, Umea, Sweden
关键词
asthma; COPD; Finland; prospective study; general population cohort; causes of death; airborne occupational exposure; job-exposure matrix; postal questionnaire; chronic lower airway disease; OBSTRUCTIVE PULMONARY-DISEASE; COPD OVERLAP SYNDROME; RESPIRATORY-DISEASES; AIRWAY-OBSTRUCTION; ASTHMA; FUMES; POPULATION; PREVALENCE; GASES; DUSTS;
D O I
10.1097/JOM.0000000000002718
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
ObjectivesOur objective was to study mortality related to different obstructive lung diseases, occupational exposure, and their potential joint effect in a large, randomized population-based cohort.MethodsWe divided the participants based on the answers to asthma and chronic obstructive pulmonary disease (COPD) diagnoses and occupational exposure and used a combined effects model and compared the results to no asthma or COPD with no occupational exposure.ResultsHigh exposure had a hazards ratio (HR) of 1.34 (1.11-1.62) and asthma and COPD coexistence of 1.58 (1.10-2.27). The combined effects of intermediate exposure and coexistence had an HR of 2.20 (1.18-4.09), high exposure with coexistence of 1.94 (1.10-3.42) for overall mortality, and sub-HR for respiratory-related mortality of 3.21 (1.87-5.50).ConclusionsHigh occupational exposure increased overall but not respiratory-related mortality hazards, while coexisting asthma and COPD overall and respiratory-related hazards of mortality.
引用
收藏
页码:22 / 28
页数:7
相关论文
共 41 条
[31]   Job titles classified into socioeconomic and occupational groups identify subjects with increased risk for respiratory symptoms independent of occupational exposure to vapour, gas, dust, or fumes [J].
Schyllert, Christian ;
Andersson, Martin ;
Hedman, Linnea ;
Ekstrom, Magnus ;
Backman, Helena ;
Lindberg, Anne ;
Ronmark, Eva .
EUROPEAN CLINICAL RESPIRATORY JOURNAL, 2018, 5
[32]   Occupational exposure to chemicals drives the increased risk of asthma and rhinitis observed for exposure to vapours, gas, dust and fumes: a cross-sectional population-based study [J].
Schyllert, Christian ;
Ronmark, Eva ;
Andersson, Martin ;
Hedlund, Ulf ;
Lundback, Bo ;
Hedman, Linnea ;
Lindberg, Anne .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2016, 73 (10) :663-669
[33]   Smoking, asthma, chronic airflow obstruction and COPD [J].
Sears, Malcolm R. .
EUROPEAN RESPIRATORY JOURNAL, 2015, 45 (03) :586-588
[34]   What is asthma-COPD overlap syndrome? Towards a consensus definition from a round table discussion [J].
Sin, Don D. ;
Miravitlles, Marc ;
Mannino, David M. ;
Soriano, Joan B. ;
Price, David ;
Celli, Bartolome R. ;
Leung, Janice M. ;
Nakano, Yasutaka ;
Park, Hye Yun ;
Wark, Peter A. ;
Wechsler, Michael E. .
EUROPEAN RESPIRATORY JOURNAL, 2016, 48 (03) :664-673
[35]   DISTINGUISHING AMONG ASTHMA, CHRONIC-BRONCHITIS, AND EMPHYSEMA [J].
SNIDER, GL .
CHEST, 1985, 87 (01) :S35-S39
[36]   Differences between asthma-COPD overlap syndrome and adult-onset asthma [J].
Tommola, Minna ;
Ilmarinen, Pinja ;
Tuomisto, Leena E. ;
Lehtimaki, Lauri ;
Haanpaa, Jussi ;
Niemela, Onni ;
Kankaanranta, Hannu .
EUROPEAN RESPIRATORY JOURNAL, 2017, 49 (05)
[37]   ASTHMA AND ASTHMA-LIKE SYMPTOMS IN ADULTS ASSESSED BY QUESTIONNAIRES - A LITERATURE-REVIEW [J].
TOREN, K ;
BRISMAN, J ;
JARVHOLM, B .
CHEST, 1993, 104 (02) :600-608
[38]   Effect of Occupational Exposure to Vapors, Gases, Dusts, and Fumes on COPD Mortality Risk Among Swedish Construction Workers A Longitudinal Cohort Study [J].
Toren, Kjell ;
Jarvholm, Bengt .
CHEST, 2014, 145 (05) :992-997
[39]   No increase in the prevalence of COPD in two decades [J].
Vasankari, T. M. ;
Impivaara, O. ;
Heliovaara, M. ;
Heistaro, S. ;
Liippo, K. ;
Puukka, P. ;
Saarelainen, S. ;
Kanervistoe, M. ;
Jousilahti, P. .
EUROPEAN RESPIRATORY JOURNAL, 2010, 36 (04) :766-773
[40]   Occupational asthma [J].
Venables, KM ;
ChanYeung, M .
LANCET, 1997, 349 (9063) :1465-1469