Mortality Associated With Occupational Exposure in Helsinki, Finland-A 24-Year Follow-up

被引：1

作者：

Jalasto, Juuso ^{[1
,2
]}

Luukkonen, Ritva ^{[3
]}

Lindqvist, Ari ^{[4
,5
]}

Langhammer, Arnulf ^{[6
,7
]}

Kankaanranta, Hannu ^{[8
,9
,10
]}

Backman, Helena ^{[11
]}

Ronmark, Eva ^{[11
]}

Sovijarvi, Anssi ^{[1
,2
]}

Kauppi, Paula ^{[4
,5
]}

Piirila, Paivi ^{[1
,2
]}

机构：

[1] Helsinki Univ Cent Hosp, HUS Med Diagnost Ctr, Dept Clin Physiol, PL 281, Helsinki 00029, Finland

[2] Univ Helsinki, PL 281, Helsinki 00029, Finland

[3] Finnish Inst Occupat Hlth, Helsinki, Finland

[4] Helsinki Univ Hosp, Heart & Lung Ctr, Dept Pulm Med, Helsinki, Finland

[5] Univ Helsinki, Helsinki, Finland

[6] Norwegian Univ Sci & Technol, HUNT Res Ctr, Dept Publ Hlth & Nursing, NTNU, Levanger, Norway

[7] Nord Trondelag Hosp Trust, Levanger Hosp, Levanger, Norway

[8] Univ Gothenburg, Inst Med, Krefting Res Ctr, Dept Internal Med & Clin Nutr, Gothenburg, Sweden

[9] Seinajoki Cent Hosp, Dept Resp Med, Seinajoki, Finland

[10] Tampere Univ, Fac Med & Hlth Technol, Resp Res Grp, Tampere, Finland

[11] Umea Univ, Dept Publ Hlth & Clin Med, OLIN Unit, Sect Sustainable Hlth, Umea, Sweden

来源：

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2023年 / 65卷 / 01期

关键词：

asthma; COPD; Finland; prospective study; general population cohort; causes of death; airborne occupational exposure; job-exposure matrix; postal questionnaire; chronic lower airway disease; OBSTRUCTIVE PULMONARY-DISEASE; COPD OVERLAP SYNDROME; RESPIRATORY-DISEASES; AIRWAY-OBSTRUCTION; ASTHMA; FUMES; POPULATION; PREVALENCE; GASES; DUSTS;

D O I：

10.1097/JOM.0000000000002718

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

ObjectivesOur objective was to study mortality related to different obstructive lung diseases, occupational exposure, and their potential joint effect in a large, randomized population-based cohort.MethodsWe divided the participants based on the answers to asthma and chronic obstructive pulmonary disease (COPD) diagnoses and occupational exposure and used a combined effects model and compared the results to no asthma or COPD with no occupational exposure.ResultsHigh exposure had a hazards ratio (HR) of 1.34 (1.11-1.62) and asthma and COPD coexistence of 1.58 (1.10-2.27). The combined effects of intermediate exposure and coexistence had an HR of 2.20 (1.18-4.09), high exposure with coexistence of 1.94 (1.10-3.42) for overall mortality, and sub-HR for respiratory-related mortality of 3.21 (1.87-5.50).ConclusionsHigh occupational exposure increased overall but not respiratory-related mortality hazards, while coexisting asthma and COPD overall and respiratory-related hazards of mortality.

引用

页码：22 / 28

页数：7

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