Argon Plasma Coagulation as Treatment for Anal Condylomas: A Narrative Review

ObjectivesAnal condylomas are a manifestation of anal human papillomavirus infection and can be associated with precancerous lesions and squamous cell carcinomas. Several methods have been described for treatment, including argon plasma coagulation. A narrative review of the evidence published on this topic was conducted.MethodsA search was conducted using PubMed, Scopus, and Web of Science databases.ResultsFive studies reported on anal/perianal condyloma treatment with argon plasma coagulation. In 3 of these studies, there was a comparison with other treatment methods (addition of imiquimod, electrofulguration, and electrocautery, respectively). Argon plasma coagulation settings varied between studies. This type of treatment was effective for ablation. Recurrence rates and follow-up times varied largely between studies. No major complications, such as pain, scarring, sexual dysfunction, or severe bleeding were described.ConclusionStudies indicate that argon plasma coagulation is an effective and safe therapy for anal and perianal condylomas.