Juvenile Idiopathic Arthritis

被引：5
作者：
Sudhakar, Murugan [1 ]
Kumar, Sathish [1 ]
机构：
[1] Christian Med Coll & Hosp, Dept Pediat, Pediat Rheumatol Div, Vellore 632004, Tamil Nadu, India
来源：
INDIAN JOURNAL OF PEDIATRICS | 2024年 / 91卷 / 09期
关键词：
Chronic arthritis; Juvenile idiopathic arthritis; Children; RHEUMATOLOGY/ARTHRITIS FOUNDATION GUIDELINE; 2019; AMERICAN-COLLEGE; RHEUMATOID-ARTHRITIS; CHILDREN; RECOMMENDATIONS; DIAGNOSIS; CLASSIFICATION; THERAPIES; EFFICACY; PROFILE;
D O I：
10.1007/s12098-023-04939-5
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. The International League of Associations for Rheumatology (ILAR) has defined JIA as "arthritis of unknown etiology persisting for >= 6 wk with an onset at <16 y of age, after excluding other causes of joint inflammation". Synovial inflammation is the result of a complex interplay of aberrant immune systems (both adaptive and innate) in a genetically susceptible individual, with possible external stimuli/triggers. Diagnosis of JIA essentially remains clinical, and laboratory investigations usually help to assess the severity of disease activity. Few investigations like antinuclear antibodies (ANA), human leukocyte antigen (HLA)-B27, and rheumatoid factor (RF) help to categorize or prognosticate a child with JIA. Timely use of effective therapeutic interventions including biological has shown good long-term outcomes of JIA.
引用
收藏
页码：949 / 958
页数：10
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