Post-COVID-19 Condition

被引：96

作者：

Nalbandian, Ani ^{[1
]}

Desai, Amar D. ^{[2
]}

Wan, Elaine Y. ^{[1
]}

机构：

[1] Columbia Univ, Dept Med, Div Cardiol, Irving Med Ctr,Vagelos Coll Phys & Surg,New York, New York, NY 10027 USA

[2] Rutgers New Jersey Med Sch, Newark, NJ USA

来源：

ANNUAL REVIEW OF MEDICINE | 2023年 / 74卷

基金：

美国国家卫生研究院;

关键词：

SARS-CoV-2; post-COVID-19; condition; postacute COVID-19 syndrome; long-haul COVID; long COVID; POST-ACUTE SEQUELAE; COVID-19; SURVIVORS; SYMPTOMS; OUTCOMES;

D O I：

10.1146/annurev-med-043021-030635

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

An estimated 10-15% of those infected with SARS-CoV-2 may have post-COVID-19 condition. Common lingering signs and symptoms include shortness of breath, fatigue, high heart rate, and memory and cognitive dysfunction even several months after infection, often impacting survivors' quality of life. The prevalence and duration of individual symptoms remain difficult to ascertain due to the lack of standardized research methods across various studies and limited patient follow-up in clinical studies. Nonetheless, data indicate post-COVID-19 condition may occur independent of acuity of initial infection, hospitalization status, age, or pre-existing comorbidities. Risk factors may include female sex and underlying respiratory or psychiatric disease. Supportive therapies to mitigate symptoms remain the mainstay of treatment. Reassuringly, most patients experience a reduction in symptoms by 1 year. The use of a universal case definition and shared research methods will allow for further clarity regarding the pervasiveness of this entity and its long-term health consequences.

引用

页码：55 / 64

页数：10

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