Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022

被引：230

作者：

Aguero, Montserrat ^{[1
]}

Monne, Isabella ^{[2
]}

Sanchez, Azucena ^{[1
]}

Zecchin, Bianca ^{[2
]}

Fusaro, Alice ^{[2
]}

Ruano, Maria Jose ^{[1
]}

Del Valle Arrojo, Manuel ^{[3
]}

Fernandez-Antonio, Ricardo ^{[4
]}

Manuel Souto, Antonio ^{[5
]}

Tordable, Pedro ^{[5
]}

Canas, Julio ^{[5
]}

Bonfante, Francesco ^{[2
]}

Giussani, Edoardo ^{[2
]}

Terregino, Calogero ^{[2
]}

Javier Orejas, Jesus ^{[6
]}

机构：

[1] Minist Agr Fisheries & Food, Lab Cent Vet LCV, Madrid, Spain

[2] Ist Zooprofilatt Sperimentale Venezie IZSVe, Legnaro, Italy

[3] Xunta Galicia, Counselling Hlth, La Coruna, Spain

[4] Galician Mink Breeders Assoc, La Coruna, Spain

[5] Xunta Galicia, Livestock Serv, Counselling Rural Affairs, La Coruna, Spain

[6] Xunta Galicia, Anim Hlth Serv, Counselling Rural Affairs, La Coruna, Spain

来源：

EUROSURVEILLANCE | 2023年 / 28卷 / 03期

关键词：

HEMAGGLUTININ;

D O I：

10.2807/1560-7917.ES.2023.28.3.2300001

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In October 2022, an outbreak in Europe of highly pathogenic avian influenza (HPAI) A(H5N1) in intensively farmed minks occurred in northwest Spain. A single mink farm hosting more than 50,000 minks was involved. The identified viruses belong to clade 2.3.4.4b, which is responsible of the ongoing epizootic in Europe. An uncommon mutation (T271A) in the PB2 gene with potential public health implications was found. Our investigations indicate onward mink transmission of the virus may have occurred in the affected farm. © 2023 European Centre for Disease Prevention and Control (ECDC). All rights reserved.

引用

页码：5 / 10

页数：6

共 17 条

[1] Avian influenza overview December 2020 - February 2021 [J].

Adlhoch, Cornelia ;

Fusaro, Alice ;

Gonzales, Jose L. ;

Kuiken, Thijs ;

Marangon, Stefano ;

Niqueux, Eric ;

Staubach, Christoph ;

Terregino, Calogero ;

Guajardo, Irene Munoz ;

Lima, Eliana ;

Baldinelli, Francesca .

EFSA JOURNAL, 2021, 19 (03)

[2] Median-joining networks for inferring intraspecific phylogenies [J].

Bandelt, HJ ;

Forster, P ;

Röhl, A .

MOLECULAR BIOLOGY AND EVOLUTION, 1999, 16 (01) :37-48

[3] PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells [J].

Bussey, Kendra A. ;

Bousse, Tatiana L. ;

Desmet, Emily A. ;

Kim, Baek ;

Takimoto, Toru .

JOURNAL OF VIROLOGY, 2010, 84 (09) :4395-4406

[4] Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR (Publication with Expression of Concern) [J].

Corman, Victor M. ;

Landt, Olfert ;

Kaiser, Marco ;

Molenkamp, Richard ;

Meijer, Adam ;

Chu, Daniel K. W. ;

Bleicker, Tobias ;

Bruenink, Sebastian ;

Schneider, Julia ;

Schmidt, Marie Luisa ;

Mulders, Daphne G. J. C. ;

Haagmans, Bart L. ;

van der Veer, Bas ;

van den Brink, Sharon ;

Wijsman, Lisa ;

Goderski, Gabriel ;

Romette, Jean-Louis ;

Ellis, Joanna ;

Zambon, Maria ;

Peiris, Malik ;

Goossens, Herman ;

Reusken, Chantal ;

Koopmans, Marion P. G. ;

Drosten, Christian .

EUROSURVEILLANCE, 2020, 25 (03) :23-30

[5]

European Commission, 2021, COMM IMPL DEC EU 202

[6] Mink, SARS-CoV-2, and the Human-Animal Interface [J].

Fenollar, Florence ;

Mediannikov, Oleg ;

Maurin, Max ;

Devaux, Christian ;

Colson, Philippe ;

Levasseur, Anthony ;

Fournier, Pierre-Edouard ;

Raoult, Didier .

FRONTIERS IN MICROBIOLOGY, 2021, 12

[7] Characterization of a Canadian Mink H3N2 Influenza A Virus Isolate Genetically Related to Triple Reassortant Swine Influenza Virus [J].

Gagnon, Carl A. ;

Spearman, Grant ;

Hamel, Andre ;

Godson, Dale L. ;

Fortin, Audrey ;

Fontaine, Guy ;

Tremblay, Donald .

JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (03) :796-799

[8] Amantadine-resistance among H5N1 avian influenza viruses isolated in Northern China [J].

He, Guimei ;

Qiao, Jian ;

Dong, Changgui ;

He, Cheng ;

Zhao, Lihong ;

Tian, Yong .

ANTIVIRAL RESEARCH, 2008, 77 (01) :72-76

[9] Riems influenza a typing array (RITA): An RT-qPCR-based low density array for subtyping avian and mammalian influenza a viruses [J].

Hoffmann, Bernd ;

Hoffmann, Donata ;

Henritzi, Dinah ;

Beer, Martin ;

Harder, Timm C. .

SCIENTIFIC REPORTS, 2016, 6

[10] Molecular characterization of highly pathogenic H5N1 avian influenza viruses isolated in Sweden in 2006 [J].

Kiss, Istvan ;

Gyarmati, Peter ;

Zohari, Siamak ;

Ramsay, Karin Wilbe ;

Metreveli, Giorgi ;

Weiss, Elisabeth ;

Brytting, Maria ;

Stivers, Marielle ;

Lindstrom, Sofia ;

Lundkvist, Ake ;

Nemirov, Kirill ;

Thoren, Peter ;

Berg, Mikael ;

Czifra, Gyorgy ;

Belak, Sandor .

VIROLOGY JOURNAL, 2008, 5 (1)

← 1 2 →