A Review of Endoscopic Ultrasound-Guided Chemoablative Techniques for Pancreatic Cystic Lesions

被引：4
作者：
Koehler, Bryn [1 ]
Ryoo, Da Yeon [1 ]
Krishna, Somashekar G. [2 ]
机构：
[1] Ohio State Univ, Wexner Med Ctr, Dept Internal Med, Columbus, OH 43210 USA
[2] Ohio State Univ, Wexner Med Ctr, Dept Internal Med, Div Gastroenterol, Columbus, OH 43210 USA
来源：
DIAGNOSTICS | 2023年 / 13卷 / 03期
关键词：
pancreatic cystic lesions; intraductal papillary mucinous neoplasms; mucinous cystic neoplasms; pancreatic cancer; EUS-FNI; EUS-guided chemoablation; LSAM-PTX; EUS-nCLE; ETHANOL-LAVAGE; MURAL NODULES; FOLLOW-UP; EUS; MANAGEMENT; ABLATION; PACLITAXEL; NEOPLASMS; DIAGNOSIS; ASSOCIATION;
D O I：
10.3390/diagnostics13030344
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pancreatic cystic lesions (PCLs) are known precursors to pancreatic cancer, one of the deadliest types of cancer worldwide. Surgical removal or pancreatectomies remain the central approach to managing precancerous high-risk PCLs. Endoscopic ultrasound (EUS)-guided therapeutic management of PCLs is a novel management strategy for patients with prohibitive surgical risks. Various ablation techniques have been explored in previous studies utilizing EUS-guided fine needle injection (FNI) of alcohol and chemotherapeutic agents. This review article focuses on EUS-FNI and chemoablation, encompassing the evolution of chemoablation, pancreatic cyst selection, chemotherapy drug selection, including novel agents, and a discussion of its safety and efficacy.
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页数：10
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