Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and Diseases

被引：5
|
作者：
Song, Juhyun [1 ]
Choi, Seok-Yong [2 ]
机构：
[1] Chonnam Natl Univ, Dept Anat, Med Sch, Hwasun 58128, South Korea
[2] Chonnam Natl Univ, Dept Biomed Sci, Med Sch, Hwasun 58128, South Korea
来源：
EXPERIMENTAL NEUROBIOLOGY | 2023年 / 32卷 / 06期
基金：
新加坡国家研究基金会;
关键词：
Arcuate nucleus; Hypothalamus; Metabolic disease; Central nervous system disease; Obesity; GONADOTROPIN-RELEASING-HORMONE; CENTRAL-NERVOUS-SYSTEM; TYROSINE-HYDROXYLASE NEURONS; Y-CONTAINING NEURONS; AMINO-ACID-SEQUENCE; NEUROPEPTIDE-Y; GROWTH-HORMONE; SUBSTANCE-P; KISSPEPTIN NEURONS; POMC NEURONS;
D O I：
10.5607/en23040
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained. As such, dysfunction of the ARH can lead to disorders of nutrition/metabolism and reproduction. Here, we review various types of neurons in the ARH and several genetic disorders caused by mutations in the ARH.
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页码：371 / 386
页数：16
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