Recent Studies on Metal-Embedded Silica Nanoparticles for Biological Applications

被引：11

作者：

Cho, Hye-Seong ^{[1
]}

Noh, Mi Suk ^{[2
]}

Kim, Yoon-Hee ^{[1
]}

Namgung, Jayoung ^{[1
]}

Yoo, Kwanghee ^{[1
]}

Shin, Min-Sup ^{[1
]}

Yang, Cho-Hee ^{[1
]}

Kim, Young Jun ^{[1
]}

Yu, Seung-Ju ^{[3
]}

Chang, Hyejin ^{[4
]}

Rho, Won Yeop ^{[3
]}

Jun, Bong-Hyun ^{[1
]}

机构：

[1] Konkuk Univ, Dept Biosci & Biotechnol, Seoul 05029, South Korea

[2] Korea Testing Certificat, Bio & Med Res Ctr, Bio Business Div, Gunpo 15809, Gyeonggi Do, South Korea

[3] Jeonbuk Natl Univ, Grad Sch Integrated Energy AI, 567 Baekje Daero, Jeonju Si 54896, Jeollabuk Do, South Korea

[4] Kangwon Natl Univ, Div Sci Educ, Chunchon 24341, South Korea

来源：

NANOMATERIALS | 2024年 / 14卷 / 03期

关键词：

surface-enhanced Raman spectroscopy (SERS); localized surface plasmon resonance (LSPR); metal nanoparticle; silica nanoparticle; core-shell structure; bio-application; GOLD NANOPARTICLES; SILVER NANOSHELLS; ELECTROSTERIC STABILIZATION; BIMETALLIC NANOPARTICLES; PHOTOTHERMAL THERAPY; SURFACE-MORPHOLOGY; DRUG-DELIVERY; SIZE; SIO2-AT-AU; CORE;

D O I：

10.3390/nano14030268

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recently, silica nanoparticles (NPs) have attracted considerable attention as biocompatible and stable templates for embedding noble metals. Noble-metal-embedded silica NPs utilize the exceptional optical properties of novel metals while overcoming the limitations of individual novel metal NPs. In addition, the structure of metal-embedded silica NPs decorated with small metal NPs around the silica core results in strong signal enhancement in localized surface plasmon resonance and surface-enhanced Raman scattering. This review summarizes recent studies on metal-embedded silica NPs, focusing on their unique designs and applications. The characteristics of the metal-embedded silica NPs depend on the type and structure of the embedded metals. Based on this progress, metal-embedded silica NPs are currently utilized in various spectroscopic applications, serving as nanozymes, detection and imaging probes, drug carriers, photothermal inducers, and bioactivation molecule screening identifiers. Owing to their versatile roles, metal-embedded silica NPs are expected to be applied in various fields, such as biology and medicine, in the future.

引用

页数：21

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