Neuroimaging findings in paediatric patients with sickle cell disease

被引：2

作者：

Abreu, V. Sousa ^{[1
]}

Xavier, S. ^{[2
]}

Santos, M. ^{[2
]}

da Silva, R. Lopes ^{[3
]}

Kjollerstrom, P. ^{[4
]}

Conceicao, C. ^{[5
]}

机构：

[1] Ctr Hosp Univ Porto, Neuroradiol Dept, Porto, Portugal

[2] Hosp Braga, Neuroradiol Dept, Braga, Portugal

[3] Hosp Dona Estefania, Ctr Hosp Univ Lisboa Cent, Paediat Neurol Unit, Lisbon, Portugal

[4] Hosp Dona Estefania, Ctr Hosp Univ Lisboa Cent, Paediat Hematol Unit, Lisbon, Portugal

[5] Ctr Hosp Univ Lisboa Cent, Neuroradiol Dept, Lisbon, Portugal

来源：

CLINICAL RADIOLOGY | 2023年 / 78卷 / 07期

关键词：

CEREBRAL FAT-EMBOLISM; MOYAMOYA-DISEASE; IMAGING PATTERNS; BONE INFARCT; STROKE RISK; CHILDREN; MANIFESTATIONS; PATHOPHYSIOLOGY; VELOCITIES; VESSELS;

D O I：

10.1016/j.crad.2023.02.013

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Sickle cell disease (SCD) is an autosomal recessive haemoglobinopathy, which manifests as multisystem ischaemia and infarction, as well as haemolytic anaemia. The morphological changes of red blood cells (RBCs) that promote ischaemia/infarction as the main multisystemic manifestation, with associated vasculopathy, may also lead to haemorrhage and fat embolisation. Bone infarctions, whether of the skull or spine, are relatively common with subsequent increased infectious susceptibility. We present a broad spectrum of brain and spine imaging findings of SCD from a level III paediatric hospital in Lisbon, between 2010 and 2022. Our aim is to highlight brain and spine imaging findings from a serial review of multiple patients with SCD and respective neuroimaging characterisation.& COPY; 2023 Published by Elsevier Ltd on behalf of The Royal College of Radiologists.

引用

页码：509 / 517

页数：9

共 43 条

[1] Long-term stroke risk in children with sickle cell disease screened with transcranial Doppler [J].