Kidney disease in patients with chronic liver disease: Does sex matter?

被引:0
作者
Cooper, Katherine M. [1 ]
Colletta, Alessandro [1 ]
Moulton, Kristen [2 ]
Ralto, Kenneth M. [3 ]
Devuni, Deepika [2 ]
机构
[1] UMass Chan Med Sch, Dept Med, 55 Lake Ave, Worcester, England
[2] UMass Chan Med Sch, Dept Med, Div Gastroenterol, Worcester, MA 01665 USA
[3] UMass Chan Med Sch, Dept Med, Div Renal Med, Worcester, MA 01665 USA
关键词
Sex differences; Renal disease; Gender disparity; Hepatorenal syndrome; Renal replacement therapy; GLOMERULAR-FILTRATION-RATE; TERLIPRESSIN PLUS ALBUMIN; HEPATORENAL-SYNDROME HRS; SERUM CYSTATIN-C; RENAL-FUNCTION; REFRACTORY ASCITES; GENDER AFFECTS; CIRRHOSIS; INJURY; MORTALITY;
D O I
10.12998/wjcc.v11.i17.3980
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Kidney disease in patients with liver disease is serious and increases mortality. Up to 50% of patients hospitalized experience an episode of acute kidney injury. In general, men with liver disease are thought to be at increased risk of kidney disease. However, this association should be considered with caution because most studies use creatinine-based inclusion criteria, which is negatively biased against women. In this review, we synthesize data on sex differences in kidney disease in patients with chronic liver disease in the clinical setting and discuss potential physiologic underpinnings.
引用
收藏
页码:3980 / 3992
页数:13
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