A rhesus macaque model of human norovirus infection

被引：0
作者：
Rimkute, Inga [1 ]
Roederer, Mario [1 ]
机构：
[1] Natl Inst Allergy & Infect Dis NIAID, Natl Inst Hlth NIH, Vaccine Res Ctr, Bethesda, MD 20892 USA
来源：
NATURE MICROBIOLOGY | 2024年 / 9卷 / 03期
关键词：
D O I：
10.1038/s41564-023-01597-3
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Human norovirus infection is a major global health concern, but a suitable animal model is lacking. We have established repeated infection with human norovirus in rhesus macaques via oral challenge. Animals demonstrate virus shedding in the stool and subsequent serum antibody responses, and virus replication is detected in the small intestine.
引用
收藏
页码：593 / 594
页数：2
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