Review on Diagnosis and Management Approach of Multiple Sclerosis

被引:1
作者
Elssayed, Ahamd [1 ]
AlRgaiba, Rana Ibrahim [2 ]
AlZalbani, Mohammed Khalid [3 ]
Hassan, Mohammed Rajab Jumah [4 ]
AlMalki, Khalid Humaid [5 ]
AlGhannam, Abdulaziz Ali [6 ]
AlMudayfir, Ziyad Fahad [7 ]
Mohamed, Hind Ali Abdourab [8 ]
Sheikh, Malak Motia [9 ]
AlGhamdi, Abdulmalek Ali [10 ]
AlMarwani, Sarah Ibrahem [11 ]
机构
[1] Dept Internal Med, Riyadh, Saudi Arabia
[2] Princess Noura Univ, Fac Med, Saudia Arabia, Riyadh, Saudi Arabia
[3] Northern Borders Univ, Fac Med, Ar Ar, Saudi Arabia
[4] ALHabib Med Grp, Fac Med, Al khobar, Saudi Arabia
[5] Tabuk Univ, Fac Med, Tabuk, Saudi Arabia
[6] King Faisal Univ, Fac Med, Al Hasa, Saudi Arabia
[7] King Saud Univ, Fac Med, Riyadh, Saudi Arabia
[8] Int Med Ctr Hosp, Fac Med, Jeddah, Saudi Arabia
[9] Taibah Univ, Fac Med, Medinah, Saudi Arabia
[10] Purchasing Dept Minist Hlth, Fac Med, Riyadh, Saudi Arabia
[11] Batterjee Med Coll, Fac Med, Jeddah, Saudi Arabia
来源
INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND ALLIED SCIENCES | 2023年 / 12卷 / 01期
关键词
Multiple sclerosis; Diagnosis; Disease course; Epidemiology; Phenotypes; Prognosis; MRI CRITERIA; GUIDELINES; THERAPY; IMMUNE; MS;
D O I
10.51847/GJcJdSPaJm
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The most prevalent non-traumatic debilitating illness affecting young individuals is multiple sclerosis (MS) (2). Both industrialized and emerging nations are seeing an increase in the incidence and prevalence of MS, whose underlying etiology is still unknown. In addition to some well-known environmental variables, such as vitamin D or ultraviolet B light (UVB) exposure, Epstein-Barr virus (EBV) infection, obesity, and smoking, MS is a complicated illness with several genes that can influence disease vulnerability (3). The Medline, Pubmed, Embase, NCBI, and Cochrane databases were searched for studies of patients with non-alcoholic fatty liver disease. Incidence, etiology, and management options were analyzed. The etiopathogenesis of MS is convoluted. The processes through which genetic and environmental risk factors for the illness alter risk are still largely unclear, despite significant improvements in their detection. Discovering these processes might result in the identification of novel and more focused therapy targets as well as disease pathways.
引用
收藏
页码:100 / 105
页数:6
相关论文
共 34 条
[1]   Environmental modifiable risk factors for multiple sclerosis: Report from the 2016 ECTRIMS focused workshop [J].
Amato, Maria Pia ;
Derfuss, Tobias ;
Hemmer, Bernard ;
Liblau, Roland ;
Montalban, Xavier ;
Sorensen, Per Soelberg ;
Miller, David H. .
MULTIPLE SCLEROSIS JOURNAL, 2018, 24 (05) :590-603
[2]   Lesion topographies in multiple sclerosis diagnosis A reappraisal [J].
Arrambide, Georgina ;
Tintore, Mar ;
Auger, Cristina ;
Rio, Jordi ;
Castillo, Joaquin ;
Vidal-Jordana, Angela ;
Galan, Ingrid ;
Nos, Carlos ;
Comabella, Manuel ;
Mitjana, Raquel ;
Mulero, Patricia ;
de Barros, Andrea ;
Rodriguez-Acevedo, Breogan ;
Midaglia, Luciana ;
Sastre-Garriga, Jaume ;
Rovira, Alex ;
Montalban, Xavier .
NEUROLOGY, 2017, 89 (23) :2351-2356
[3]   Environmental factors in multiple sclerosis [J].
Ascherio, Alberto .
EXPERT REVIEW OF NEUROTHERAPEUTICS, 2013, 13 (12) :3-9
[4]   Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses [J].
Belbasis, Lazaros ;
Bellou, Vanesa ;
Evangelou, Evangelos ;
Ioannidis, John P. A. ;
Tzoulaki, Ioanna .
LANCET NEUROLOGY, 2015, 14 (03) :263-273
[5]   ATLAS OF MULTIPLE SCLEROSIS 2013: A GROWING GLOBAL PROBLEM WITH WIDESPREAD INEQUITY [J].
Browne, Paul ;
Chandraratna, Dhia ;
Angood, Ceri ;
Tremlett, Helen ;
Baker, Chris ;
Taylor, Bruce V. ;
Thompson, Alan J. .
NEUROLOGY, 2014, 83 (11) :1022-1024
[6]   Diagnosis of multiple sclerosis: progress and challenges [J].
Brownlee, Wallace J. ;
Hardy, Todd A. ;
Fazekas, Franz ;
Miller, David H. .
LANCET, 2017, 389 (10076) :1336-1346
[7]   Multiple Sclerosis Epidemiology in East Asia, South East Asia and South Asia: A Systematic Review [J].
Eskandarieh, Sharareh ;
Heydarpour, Pouria ;
Minagar, Alireza ;
Pourmand, Shadi ;
Sahraian, Mohammad Ali .
NEUROEPIDEMIOLOGY, 2016, 46 (03) :209-221
[8]   MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines [J].
Filippi, Massimo ;
Rocca, Maria A. ;
Ciccarelli, Olga ;
De Stefano, Nicola ;
Evangelou, Nikos ;
Kappos, Ludwig ;
Rovira, Alex ;
Sastre-Garriga, Jaume ;
Tintore, Mar ;
Frederiksen, Jette L. ;
Gasperini, Claudio ;
Palace, Jacqueline ;
Reich, Daniel S. ;
Banwell, Brenda ;
Montalban, Xavier ;
Barkhof, Frederik .
LANCET NEUROLOGY, 2016, 15 (03) :292-303
[9]   Is multiple sclerosis a length-dependent central axonopathy? The case for therapeutic lag and the asynchronous progressive MS hypotheses [J].
Giovannoni, Gavin ;
Cutter, Gary ;
Pia-Sormani, Maria ;
Belachew, Shibeshih ;
Hyde, Robert ;
Koendgen, Harold ;
Knappertz, Volker ;
Tomic, Davorka ;
Leppert, David ;
Herndon, Robert ;
Wheeler-Kingshott, Claudia A. M. ;
Ciccarelli, Olga ;
Selwood, David ;
di Cantogno, Elisabetta Verdun ;
Ben-Amor, Ali-Frederic ;
Matthews, Paul ;
Carassiti, Daniele ;
Baker, David ;
Schmierer, Klaus .
MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2017, 12 :70-78
[10]   B-Cell Therapy for Multiple Sclerosis: Entering an Era [J].
Greenfield, Ariele L. ;
Hauser, Stephen L. .
ANNALS OF NEUROLOGY, 2018, 83 (01) :13-26