Metal-free and site-selective α-C-H functionalization of tetrahydrofuran enabled by the photocatalytic generation of bromine radicals

被引：32

作者：

Zhu, Can-Ming ^{[1
,2
,3
]}

Liang, Rong-Bin ^{[1
,2
,3
]}

Xiao, Yonghong ^{[1
,2
,3
]}

Zhou, Wei ^{[1
,2
,3
]}

Tong, Qing-Xiao ^{[1
,2
,3
]}

Zhong, Jian-Ji ^{[1
,2
,3
]}

机构：

[1] Shantou Univ, Dept Chem, Peoples R China, Shantou 515063, Guangdong, Peoples R China

[2] Shantou Univ, Key Lab Preparat & Applicat Ordered Struct Mat Gua, Shantou 515063, Guangdong, Peoples R China

[3] Chem & Chem Engn Guangdong Lab, Shantou 515063, Guangdong, Peoples R China

来源：

GREEN CHEMISTRY | 2023年 / 25卷 / 03期

基金：

中国国家自然科学基金;

关键词：

PHOTOREDOX CATALYSIS; BONDS ADJACENT; ETHERS; ACTIVATION; ARYLATION; MILD; OXIDATION; AMIDES;

D O I：

10.1039/d2gc03347j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first example of using commercially available and cheap (Bu4NBr)-Bu-n as a cocatalyst, which is photoactivated by 4-CzIPN, to selectively activate the alpha-C-H bond of tetrahydrofuran for C-S and C-C cross-couplings is reported herein. This transition-metal free strategy features operational simplicity, mild and inherent green conditions as well as broad substrate scope.

引用

页码：960 / 965

页数：7

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